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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GUCA1B All Species: 22.73
Human Site: Y57 Identified Species: 38.46
UniProt: Q9UMX6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UMX6 NP_002089.4 200 23420 Y57 D D E E A S Q Y V E G M F R A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086886 202 22999 Y55 L S P S A S Q Y V E Q M F E T
Dog Lupus familis XP_538922 201 23483 Y57 G N E E A T Q Y V E G M F R A
Cat Felis silvestris
Mouse Mus musculus Q8VBV8 201 23501 Y57 G N E E A S Q Y V E S M F R A
Rat Rattus norvegicus P62749 193 22320 F64 P Y G D A S K F A E H V F R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508360 199 23044 Y57 E N K E A T E Y L E S M F R A
Chicken Gallus gallus P79881 198 23110 Y56 D N H E A A E Y I E N M F R A
Frog Xenopus laevis Q6DCM9 193 22267 F64 P Y G D A S K F A E H V F R T
Zebra Danio Brachydanio rerio Q6AXL4 192 21965 F64 P Y G D A S K F A E H V F R T
Tiger Blowfish Takifugu rubipres NP_001027857 197 22910 Y56 E N K E A A D Y I E N M F R A
Fruit Fly Dros. melanogaster P42325 190 21875 F64 P Y G D A S K F A E H V F R T
Honey Bee Apis mellifera XP_392256 192 21952 F64 P Y G D A S K F A E H V F R T
Nematode Worm Caenorhab. elegans P36608 191 22003 F64 P Q G D P S D F A S F V F K V
Sea Urchin Strong. purpuratus XP_783112 194 22350 F64 P Y G D A S K F A E H V F R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 45.5 88.5 N.A. 88 43 N.A. 78.5 77.5 43 43 76 42.5 44 35.5 42.5
Protein Similarity: 100 N.A. 63.3 96.5 N.A. 93.5 61 N.A. 88 89 61 60.5 86 60 62.5 56.5 61
P-Site Identity: 100 N.A. 53.3 80 N.A. 80 33.3 N.A. 53.3 60 33.3 33.3 53.3 33.3 33.3 13.3 33.3
P-Site Similarity: 100 N.A. 53.3 93.3 N.A. 86.6 60 N.A. 93.3 86.6 60 60 86.6 60 60 40 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 93 15 0 0 50 0 0 0 0 0 43 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 8 0 50 0 0 15 0 0 0 0 0 0 0 0 % D
% Glu: 15 0 22 43 0 0 15 0 0 93 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 50 0 0 8 0 100 0 0 % F
% Gly: 15 0 50 0 0 0 0 0 0 0 15 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 0 43 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % I
% Lys: 0 0 15 0 0 0 43 0 0 0 0 0 0 8 0 % K
% Leu: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % M
% Asn: 0 36 0 0 0 0 0 0 0 0 15 0 0 0 0 % N
% Pro: 50 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 29 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 86 0 % R
% Ser: 0 8 0 8 0 72 0 0 0 8 15 0 0 0 0 % S
% Thr: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 50 % T
% Val: 0 0 0 0 0 0 0 0 29 0 0 50 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 43 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _