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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC45A2 All Species: 5.76
Human Site: Y266 Identified Species: 11.52
UniProt: Q9UMX9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UMX9 NP_057264.3 530 58268 Y266 P L S S D G M Y E Y G S I E K
Chimpanzee Pan troglodytes XP_526962 530 58226 Y266 P L S S D G M Y E Y G S I E K
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P58355 530 57943 H266 S L S A S G M H E Y G S I E K
Rat Rattus norvegicus Q8K4S3 751 81734 L317 L P P S P P V L L E E G A G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512451 297 32418 E48 R E F C Y A V E A A F V T P V
Chicken Gallus gallus NP_001076833 543 59420 E284 X K Y R S I E E I K N G Y S S
Frog Xenopus laevis NP_001089379 548 60292 K286 G A Y G S I D K T Q N G I L K
Zebra Danio Brachydanio rerio NP_001103847 554 60448 Y288 E G P L Q N G Y G S V C K E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648292 599 66040 K314 I K K E L K K K N N T I Y Y I
Honey Bee Apis mellifera XP_623536 615 68098 Y330 V C L I L I N Y S S I L E H E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782027 672 72693 D354 D E N E N D G D I D E T S P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O80605 594 63954 E307 D L Q S K G L E H S K L N N G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 N.A. N.A. N.A. 81.8 32 N.A. 40.3 63.9 67.1 59.9 N.A. 30.8 30.7 N.A. 31.5
Protein Similarity: 100 99.2 N.A. N.A. N.A. 88.6 46.7 N.A. 48.2 75.1 77 72.7 N.A. 51.2 46.6 N.A. 48.6
P-Site Identity: 100 100 N.A. N.A. N.A. 73.3 6.6 N.A. 0 0 13.3 13.3 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. N.A. N.A. 86.6 13.3 N.A. 6.6 0 13.3 13.3 N.A. 0 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 22.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 9 0 0 9 9 0 0 9 0 0 % A
% Cys: 0 9 0 9 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 17 0 0 0 17 9 9 9 0 9 0 0 0 0 9 % D
% Glu: 9 17 0 17 0 0 9 25 25 9 17 0 9 34 9 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 9 9 0 9 0 34 17 0 9 0 25 25 0 9 9 % G
% His: 0 0 0 0 0 0 0 9 9 0 0 0 0 9 0 % H
% Ile: 9 0 0 9 0 25 0 0 17 0 9 9 34 0 9 % I
% Lys: 0 17 9 0 9 9 9 17 0 9 9 0 9 0 34 % K
% Leu: 9 34 9 9 17 0 9 9 9 0 0 17 0 9 9 % L
% Met: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 9 9 9 0 9 9 17 0 9 9 0 % N
% Pro: 17 9 17 0 9 9 0 0 0 0 0 0 0 17 9 % P
% Gln: 0 0 9 0 9 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 9 0 25 34 25 0 0 0 9 25 0 25 9 9 9 % S
% Thr: 0 0 0 0 0 0 0 0 9 0 9 9 9 0 0 % T
% Val: 9 0 0 0 0 0 17 0 0 0 9 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 17 0 9 0 0 34 0 25 0 0 17 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _