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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPRQ All Species: 14.55
Human Site: S2221 Identified Species: 40
UniProt: Q9UMZ3 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UMZ3 NP_001138498.1 2332 260924 S2221 F V K L V R A S R A H D T T P
Chimpanzee Pan troglodytes XP_001151129 2765 310146 S2654 F V K L V R A S R A H D T T P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539698 2581 288181 N2414 G N E D R I C N G P L K P K K
Cat Felis silvestris
Mouse Mus musculus P0C5E4 2300 256766 S2189 F V K L V R T S R A H D A T P
Rat Rattus norvegicus O88488 2302 256806 S2191 F V K L V R T S R A H D T T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512269 2148 240953 V2038 L I Q F V R T V R D Y V N R T
Chicken Gallus gallus Q9W6V5 1406 154195 S1296 H L V H E Y S S Q N P I D S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4IFW2 1909 213435 Q1799 G Q S R T I R Q F Q F T D W P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16621 2029 229038 Q1919 G S S R T V R Q F Q F I D W P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 N.A. 67.3 N.A. 85 84.7 N.A. 21.7 22.1 N.A. 20.5 N.A. 21.4 N.A. N.A. N.A.
Protein Similarity: 100 83.9 N.A. 72.1 N.A. 91.8 91.9 N.A. 39.4 36.3 N.A. 37.2 N.A. 39.5 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 0 N.A. 86.6 93.3 N.A. 20 13.3 N.A. 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 13.3 N.A. 86.6 93.3 N.A. 40 40 N.A. 6.6 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 23 0 0 45 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 0 0 0 0 12 0 45 34 0 0 % D
% Glu: 0 0 12 0 12 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 45 0 0 12 0 0 0 0 23 0 23 0 0 0 0 % F
% Gly: 34 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % G
% His: 12 0 0 12 0 0 0 0 0 0 45 0 0 0 0 % H
% Ile: 0 12 0 0 0 23 0 0 0 0 0 23 0 0 0 % I
% Lys: 0 0 45 0 0 0 0 0 0 0 0 12 0 12 12 % K
% Leu: 12 12 0 45 0 0 0 0 0 0 12 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 12 0 12 0 0 12 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 12 12 0 12 0 78 % P
% Gln: 0 12 12 0 0 0 0 23 12 23 0 0 0 0 0 % Q
% Arg: 0 0 0 23 12 56 23 0 56 0 0 0 0 12 0 % R
% Ser: 0 12 23 0 0 0 12 56 0 0 0 0 0 12 0 % S
% Thr: 0 0 0 0 23 0 34 0 0 0 0 12 34 45 12 % T
% Val: 0 45 12 0 56 12 0 12 0 0 0 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 0 % W
% Tyr: 0 0 0 0 0 12 0 0 0 0 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _