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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDRG2 All Species: 28.18
Human Site: Y217 Identified Species: 62
UniProt: Q9UN36 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UN36 NP_057334.1 371 40798 Y217 N S E L I Q K Y R N I I T H A
Chimpanzee Pan troglodytes A5A6K6 357 39342 Y203 N S E L I Q K Y R N I I T H A
Rhesus Macaque Macaca mulatta XP_001095407 328 35491 A181 Y R N I I T H A P N L D N I E
Dog Lupus familis XP_851185 371 40699 Y217 N S E L I Q K Y R N I I T H A
Cat Felis silvestris
Mouse Mus musculus Q9QYG0 371 40771 Y217 N S E L I Q K Y R G I I Q H A
Rat Rattus norvegicus Q8VBU2 371 40761 Y217 N S E L I Q K Y R S L I T H A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516771 363 39956 Y212 S S E L V Q R Y R E V I V H A
Chicken Gallus gallus XP_001231665 515 55908 Y350 N T E L V Q S Y R Q Q I G S V
Frog Xenopus laevis Q7ZY73 360 39367 Y213 N S D V V R Q Y K A S I S N S
Zebra Danio Brachydanio rerio Q5PR98 368 40449 H217 N T E L I Q T H R E R I T K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02485 325 35573 G178 Y L L A H K F G G E S K S R Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.6 80.3 96.5 N.A. 95.6 95.9 N.A. 84.3 45.6 72.7 69.2 N.A. N.A. N.A. 24.7 N.A.
Protein Similarity: 100 95.9 83 98.1 N.A. 98.1 98.9 N.A. 90.3 57.4 85.4 84 N.A. N.A. N.A. 43.9 N.A.
P-Site Identity: 100 100 13.3 100 N.A. 86.6 86.6 N.A. 60 46.6 26.6 60 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 86.6 100 N.A. 86.6 60 86.6 73.3 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 10 0 10 0 0 0 0 64 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 73 0 0 0 0 0 0 28 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 10 10 0 0 10 0 0 % G
% His: 0 0 0 0 10 0 10 10 0 0 0 0 0 55 0 % H
% Ile: 0 0 0 10 64 0 0 0 0 0 37 82 0 10 0 % I
% Lys: 0 0 0 0 0 10 46 0 10 0 0 10 0 10 0 % K
% Leu: 0 10 10 73 0 0 0 0 0 0 19 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 73 0 10 0 0 0 0 0 0 37 0 0 10 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 73 10 0 0 10 10 0 10 0 10 % Q
% Arg: 0 10 0 0 0 10 10 0 73 0 10 0 0 10 0 % R
% Ser: 10 64 0 0 0 0 10 0 0 10 19 0 19 10 10 % S
% Thr: 0 19 0 0 0 10 10 0 0 0 0 0 46 0 0 % T
% Val: 0 0 0 10 28 0 0 0 0 0 10 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 0 0 0 0 0 0 73 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _