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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4A
All Species:
32.73
Human Site:
S199
Identified Species:
51.43
UniProt:
Q9UN37
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN37
NP_037377.1
437
48898
S199
V
S
S
S
D
L
M
S
K
W
L
G
E
S
E
Chimpanzee
Pan troglodytes
XP_001147558
511
57412
S273
V
S
S
S
D
L
M
S
K
W
L
G
E
S
E
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
S278
V
S
S
S
D
L
M
S
K
W
L
G
E
S
E
Dog
Lupus familis
XP_536805
437
48918
S199
V
S
S
S
D
L
M
S
K
W
L
G
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ9
437
48888
S199
V
S
S
S
D
L
M
S
K
W
L
G
E
S
E
Rat
Rattus norvegicus
Q5XIK7
488
55183
K215
I
A
D
L
E
E
A
K
K
L
L
R
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
S246
V
S
S
S
D
L
M
S
K
W
L
G
E
S
E
Chicken
Gallus gallus
Q1HGK7
492
56020
T186
E
P
K
K
F
D
S
T
G
Y
D
K
D
L
V
Frog
Xenopus laevis
Q9PUL2
486
55412
K215
I
A
D
L
E
E
A
K
K
L
L
K
E
A
V
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
I208
P
N
I
H
W
D
D
I
A
D
L
E
D
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573258
442
49577
S204
V
S
S
S
D
L
M
S
K
W
L
G
E
S
E
Honey Bee
Apis mellifera
XP_393250
441
49311
S203
V
S
S
S
D
L
V
S
K
W
L
G
E
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
K243
I
A
G
L
T
E
A
K
R
L
L
E
E
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
D203
K
A
E
S
M
N
G
D
A
E
D
G
K
S
K
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
K205
S
S
S
D
L
V
S
K
W
M
G
E
S
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
84.5
98.8
N.A.
99
36.4
N.A.
83.2
37.4
37.2
35.4
N.A.
74.2
77
N.A.
34.5
Protein Similarity:
100
85.3
84.6
99.7
N.A.
100
55.5
N.A.
87.1
54.2
55.7
56.7
N.A.
85.9
88.8
N.A.
52.3
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
100
0
20
6.6
N.A.
100
93.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
100
20
46.6
33.3
N.A.
100
100
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
27
0
0
0
0
20
0
14
0
0
0
0
27
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
14
7
54
14
7
7
0
7
14
0
14
0
0
% D
% Glu:
7
0
7
0
14
20
0
0
0
7
0
20
74
7
54
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
7
0
7
0
7
60
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% I
% Lys:
7
0
7
7
0
0
0
27
67
0
0
14
7
0
20
% K
% Leu:
0
0
0
20
7
54
0
0
0
20
80
0
0
7
0
% L
% Met:
0
0
0
0
7
0
47
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% R
% Ser:
7
60
60
60
0
0
14
54
0
0
0
0
7
60
0
% S
% Thr:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% T
% Val:
54
0
0
0
0
7
7
0
0
0
0
0
0
0
27
% V
% Trp:
0
0
0
0
7
0
0
0
7
54
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _