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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4A
All Species:
30.91
Human Site:
S241
Identified Species:
48.57
UniProt:
Q9UN37
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN37
NP_037377.1
437
48898
S241
G
S
R
N
E
N
E
S
E
A
A
R
R
I
K
Chimpanzee
Pan troglodytes
XP_001147558
511
57412
S315
G
S
R
N
E
N
E
S
E
A
A
R
R
I
K
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
S320
G
S
R
N
E
N
E
S
E
A
A
R
R
I
K
Dog
Lupus familis
XP_536805
437
48918
S241
G
S
R
N
E
N
E
S
E
A
A
R
R
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ9
437
48888
S241
G
S
R
N
E
N
E
S
E
A
A
R
R
I
K
Rat
Rattus norvegicus
Q5XIK7
488
55183
L275
F
N
V
S
S
S
T
L
T
S
K
Y
R
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
S288
G
S
R
N
E
N
E
S
E
A
A
R
R
I
K
Chicken
Gallus gallus
Q1HGK7
492
56020
L279
F
N
V
S
S
S
T
L
T
S
K
Y
R
G
E
Frog
Xenopus laevis
Q9PUL2
486
55412
L275
F
N
I
S
S
S
T
L
T
S
K
Y
R
G
E
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
L275
F
N
V
S
S
S
T
L
T
S
K
Y
R
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573258
442
49577
N246
S
A
R
S
D
N
E
N
D
S
V
R
R
I
K
Honey Bee
Apis mellifera
XP_393250
441
49311
S245
S
S
R
S
D
N
E
S
E
S
A
R
R
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
L303
F
N
V
S
S
A
S
L
T
S
K
Y
H
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
L308
F
N
V
S
S
A
T
L
A
S
K
W
R
G
E
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
S246
G
T
R
G
E
G
E
S
E
A
S
R
R
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
84.5
98.8
N.A.
99
36.4
N.A.
83.2
37.4
37.2
35.4
N.A.
74.2
77
N.A.
34.5
Protein Similarity:
100
85.3
84.6
99.7
N.A.
100
55.5
N.A.
87.1
54.2
55.7
56.7
N.A.
85.9
88.8
N.A.
52.3
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
6.6
6.6
6.6
N.A.
46.6
73.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
100
40
40
40
N.A.
86.6
93.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
14
0
0
7
47
47
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
14
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
47
0
60
0
54
0
0
0
0
0
40
% E
% Phe:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
47
0
0
7
0
7
0
0
0
0
0
0
0
40
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
0
60
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
40
0
0
0
60
% K
% Leu:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
40
0
40
0
54
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
60
0
0
0
0
0
0
0
0
60
94
0
0
% R
% Ser:
14
47
0
54
40
27
7
54
0
54
7
0
0
0
0
% S
% Thr:
0
7
0
0
0
0
34
0
34
0
0
0
0
0
0
% T
% Val:
0
0
34
0
0
0
0
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _