KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4A
All Species:
37.88
Human Site:
S279
Identified Species:
59.52
UniProt:
Q9UN37
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN37
NP_037377.1
437
48898
S279
N
I
P
W
V
L
D
S
A
I
R
R
R
F
E
Chimpanzee
Pan troglodytes
XP_001147558
511
57412
S353
N
I
P
W
V
L
D
S
A
I
R
R
R
F
E
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
S358
N
I
P
W
V
L
D
S
A
I
R
R
R
F
E
Dog
Lupus familis
XP_536805
437
48918
S279
N
I
P
W
V
L
D
S
A
I
R
R
R
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ9
437
48888
S279
N
I
P
W
V
L
D
S
A
I
R
R
R
F
E
Rat
Rattus norvegicus
Q5XIK7
488
55183
A322
G
T
S
D
E
H
E
A
S
R
R
V
K
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
S326
N
I
P
W
V
L
D
S
A
I
R
R
R
F
E
Chicken
Gallus gallus
Q1HGK7
492
56020
A326
G
T
S
E
E
H
E
A
S
R
R
V
K
A
E
Frog
Xenopus laevis
Q9PUL2
486
55412
A322
G
T
S
E
E
H
E
A
S
R
R
V
K
A
E
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
A322
G
T
S
D
E
H
E
A
S
R
R
V
K
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573258
442
49577
S284
N
I
P
W
V
L
D
S
A
I
R
R
R
F
E
Honey Bee
Apis mellifera
XP_393250
441
49311
S283
N
I
P
W
V
L
D
S
A
I
R
R
R
F
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
A350
G
T
G
S
E
H
E
A
S
R
R
V
K
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
S355
G
G
S
G
E
H
E
S
S
R
R
V
K
S
E
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
S284
N
I
P
W
Q
L
D
S
A
I
R
R
R
F
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
84.5
98.8
N.A.
99
36.4
N.A.
83.2
37.4
37.2
35.4
N.A.
74.2
77
N.A.
34.5
Protein Similarity:
100
85.3
84.6
99.7
N.A.
100
55.5
N.A.
87.1
54.2
55.7
56.7
N.A.
85.9
88.8
N.A.
52.3
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
100
13.3
13.3
13.3
N.A.
100
100
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
100
40
40
40
N.A.
100
100
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
93.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
34
60
0
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
14
0
0
60
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
14
40
0
40
0
0
0
0
0
0
0
100
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% F
% Gly:
40
7
7
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
60
0
0
0
0
0
0
0
60
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% K
% Leu:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
40
100
60
60
0
0
% R
% Ser:
0
0
34
7
0
0
0
67
40
0
0
0
0
27
0
% S
% Thr:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
54
0
0
0
0
0
0
40
0
0
0
% V
% Trp:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _