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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4A
All Species:
22.12
Human Site:
S309
Identified Species:
34.76
UniProt:
Q9UN37
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN37
NP_037377.1
437
48898
S309
M
F
R
L
H
L
G
S
T
P
H
N
L
T
D
Chimpanzee
Pan troglodytes
XP_001147558
511
57412
S383
M
F
R
L
H
L
G
S
T
P
H
N
L
T
D
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
S388
M
F
R
L
H
L
G
S
T
P
H
N
L
T
D
Dog
Lupus familis
XP_536805
437
48918
S309
M
F
R
L
H
L
G
S
T
P
H
N
L
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ9
437
48888
S309
M
F
R
L
H
L
G
S
T
P
H
N
L
T
D
Rat
Rattus norvegicus
Q5XIK7
488
55183
A354
S
K
M
V
M
V
L
A
A
T
N
F
P
W
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
N356
M
F
R
L
H
L
G
N
T
P
H
S
L
S
E
Chicken
Gallus gallus
Q1HGK7
492
56020
A358
S
K
M
V
M
V
L
A
A
T
N
F
P
W
D
Frog
Xenopus laevis
Q9PUL2
486
55412
A354
S
K
M
V
M
V
L
A
A
T
N
F
P
W
D
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
A354
S
K
M
V
M
V
L
A
A
T
N
F
P
W
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573258
442
49577
N314
M
F
K
I
H
L
G
N
T
T
H
V
L
T
E
Honey Bee
Apis mellifera
XP_393250
441
49311
S313
M
F
K
I
H
L
G
S
T
S
H
C
L
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
A382
S
K
M
V
M
V
L
A
A
T
N
F
P
W
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
N391
V
M
V
L
A
A
T
N
F
P
W
D
I
D
E
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
I310
A
R
T
T
M
F
E
I
N
V
G
D
T
P
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
84.5
98.8
N.A.
99
36.4
N.A.
83.2
37.4
37.2
35.4
N.A.
74.2
77
N.A.
34.5
Protein Similarity:
100
85.3
84.6
99.7
N.A.
100
55.5
N.A.
87.1
54.2
55.7
56.7
N.A.
85.9
88.8
N.A.
52.3
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
73.3
6.6
6.6
6.6
N.A.
60
66.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
100
33.3
33.3
33.3
N.A.
86.6
86.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
7
0
34
34
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
14
0
7
67
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
27
% E
% Phe:
0
54
0
0
0
7
0
0
7
0
0
34
0
0
0
% F
% Gly:
0
0
0
0
0
0
54
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
54
0
0
0
0
0
54
0
0
0
0
% H
% Ile:
0
0
0
14
0
0
0
7
0
0
0
0
7
0
0
% I
% Lys:
0
34
14
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
47
0
54
34
0
0
0
0
0
54
0
0
% L
% Met:
54
7
34
0
40
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
20
7
0
34
34
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
47
0
0
34
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
40
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
34
0
0
0
0
0
0
40
0
7
0
7
0
7
0
% S
% Thr:
0
0
7
7
0
0
7
0
54
40
0
0
7
47
0
% T
% Val:
7
0
7
34
0
34
0
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
34
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _