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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4A
All Species:
23.03
Human Site:
S97
Identified Species:
36.19
UniProt:
Q9UN37
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN37
NP_037377.1
437
48898
S97
S
E
G
K
G
S
D
S
D
S
E
G
D
N
P
Chimpanzee
Pan troglodytes
XP_001147558
511
57412
S171
S
E
G
K
G
S
D
S
D
S
E
G
D
N
P
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
S176
S
E
G
K
G
S
D
S
D
S
E
G
D
N
P
Dog
Lupus familis
XP_536805
437
48918
S97
S
E
S
K
G
S
D
S
D
S
E
G
D
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ9
437
48888
S97
S
E
G
K
G
S
D
S
D
S
E
G
D
N
P
Rat
Rattus norvegicus
Q5XIK7
488
55183
A105
V
W
P
P
P
V
P
A
E
H
R
A
P
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
S144
N
D
N
K
G
S
D
S
D
S
E
G
E
N
P
Chicken
Gallus gallus
Q1HGK7
492
56020
V97
L
P
A
H
D
A
E
V
W
S
L
P
V
P
A
Frog
Xenopus laevis
Q9PUL2
486
55412
V97
F
P
S
H
D
G
E
V
W
S
L
P
V
P
V
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
A105
V
W
P
P
P
T
P
A
E
H
R
G
P
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573258
442
49577
K98
A
K
D
D
K
D
K
K
S
D
S
D
D
E
D
Honey Bee
Apis mellifera
XP_393250
441
49311
D98
K
T
E
D
K
K
S
D
S
G
D
S
D
T
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
Q130
H
R
P
S
P
P
Y
Q
R
A
A
R
K
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
S99
S
P
P
I
N
T
K
S
S
F
V
F
Q
P
L
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
K97
S
G
S
N
G
G
N
K
K
I
S
Q
E
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
84.5
98.8
N.A.
99
36.4
N.A.
83.2
37.4
37.2
35.4
N.A.
74.2
77
N.A.
34.5
Protein Similarity:
100
85.3
84.6
99.7
N.A.
100
55.5
N.A.
87.1
54.2
55.7
56.7
N.A.
85.9
88.8
N.A.
52.3
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
73.3
6.6
6.6
6.6
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
13.3
N.A.
93.3
20
13.3
26.6
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
7
0
14
0
7
7
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
14
14
7
40
7
40
7
7
7
47
7
14
% D
% Glu:
0
34
7
0
0
0
14
0
14
0
40
0
14
14
0
% E
% Phe:
7
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% F
% Gly:
0
7
27
0
47
14
0
0
0
7
0
47
0
0
7
% G
% His:
7
0
0
14
0
0
0
0
0
14
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
7
7
0
40
14
7
14
14
7
0
0
0
7
0
0
% K
% Leu:
7
0
0
0
0
0
0
0
0
0
14
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
7
7
0
7
0
0
0
0
0
0
40
0
% N
% Pro:
0
20
27
14
20
7
14
0
0
0
0
14
14
27
47
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
7
7
0
14
% Q
% Arg:
0
7
0
0
0
0
0
0
7
0
14
7
0
0
0
% R
% Ser:
47
0
20
7
0
40
7
47
20
54
14
7
0
0
0
% S
% Thr:
0
7
0
0
0
14
0
0
0
0
0
0
0
7
0
% T
% Val:
14
0
0
0
0
7
0
14
0
0
7
0
14
7
7
% V
% Trp:
0
14
0
0
0
0
0
0
14
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _