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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4A
All Species:
24.85
Human Site:
S99
Identified Species:
39.05
UniProt:
Q9UN37
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN37
NP_037377.1
437
48898
S99
G
K
G
S
D
S
D
S
E
G
D
N
P
E
K
Chimpanzee
Pan troglodytes
XP_001147558
511
57412
S173
G
K
G
S
D
S
D
S
E
G
D
N
P
E
K
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
S178
G
K
G
S
D
S
D
S
E
G
D
N
P
E
K
Dog
Lupus familis
XP_536805
437
48918
S99
S
K
G
S
D
S
D
S
E
G
D
N
P
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ9
437
48888
S99
G
K
G
S
D
S
D
S
E
G
D
N
P
E
K
Rat
Rattus norvegicus
Q5XIK7
488
55183
H107
P
P
P
V
P
A
E
H
R
A
P
P
Q
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
S146
N
K
G
S
D
S
D
S
E
G
E
N
P
E
K
Chicken
Gallus gallus
Q1HGK7
492
56020
S99
A
H
D
A
E
V
W
S
L
P
V
P
A
E
R
Frog
Xenopus laevis
Q9PUL2
486
55412
S99
S
H
D
G
E
V
W
S
L
P
V
P
V
E
R
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
H107
P
P
P
T
P
A
E
H
R
G
P
V
Q
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573258
442
49577
D100
D
D
K
D
K
K
S
D
S
D
D
E
D
G
D
Honey Bee
Apis mellifera
XP_393250
441
49311
G100
E
D
K
K
S
D
S
G
D
S
D
T
D
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
A132
P
S
P
P
Y
Q
R
A
A
R
K
D
P
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
F101
P
I
N
T
K
S
S
F
V
F
Q
P
L
D
E
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
I99
S
N
G
G
N
K
K
I
S
Q
E
E
G
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
84.5
98.8
N.A.
99
36.4
N.A.
83.2
37.4
37.2
35.4
N.A.
74.2
77
N.A.
34.5
Protein Similarity:
100
85.3
84.6
99.7
N.A.
100
55.5
N.A.
87.1
54.2
55.7
56.7
N.A.
85.9
88.8
N.A.
52.3
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
86.6
13.3
13.3
13.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
20
N.A.
93.3
33.3
26.6
33.3
N.A.
6.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
14
0
7
7
7
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
14
7
40
7
40
7
7
7
47
7
14
7
20
% D
% Glu:
7
0
0
0
14
0
14
0
40
0
14
14
0
60
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% F
% Gly:
27
0
47
14
0
0
0
7
0
47
0
0
7
7
0
% G
% His:
0
14
0
0
0
0
0
14
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
7
0
0
0
0
0
7
0
% I
% Lys:
0
40
14
7
14
14
7
0
0
0
7
0
0
0
47
% K
% Leu:
0
0
0
0
0
0
0
0
14
0
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
7
0
7
0
0
0
0
0
0
40
0
0
0
% N
% Pro:
27
14
20
7
14
0
0
0
0
14
14
27
47
7
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
7
7
0
14
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
14
7
0
0
0
0
27
% R
% Ser:
20
7
0
40
7
47
20
54
14
7
0
0
0
7
0
% S
% Thr:
0
0
0
14
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
7
0
14
0
0
7
0
14
7
7
7
0
% V
% Trp:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _