KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4A
All Species:
27.27
Human Site:
T375
Identified Species:
42.86
UniProt:
Q9UN37
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN37
NP_037377.1
437
48898
T375
M
M
I
D
D
L
L
T
P
C
S
P
G
D
P
Chimpanzee
Pan troglodytes
XP_001147558
511
57412
T449
M
M
I
D
D
L
L
T
P
C
S
P
G
D
P
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
T454
V
M
I
D
D
L
L
T
P
C
S
P
G
D
P
Dog
Lupus familis
XP_536805
437
48918
T375
V
M
I
D
D
L
L
T
P
C
S
P
G
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ9
437
48888
T375
V
M
I
D
D
L
L
T
P
C
S
P
G
D
P
Rat
Rattus norvegicus
Q5XIK7
488
55183
N420
Y
S
G
A
D
I
T
N
I
C
R
D
A
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
T422
I
I
I
D
D
L
L
T
P
C
S
P
G
D
P
Chicken
Gallus gallus
Q1HGK7
492
56020
N424
Y
S
G
A
D
I
T
N
V
C
R
D
A
S
L
Frog
Xenopus laevis
Q9PUL2
486
55412
N420
Y
S
G
A
D
I
T
N
V
C
R
D
A
S
L
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
N420
Y
S
G
A
D
I
T
N
V
C
R
D
A
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573258
442
49577
V380
E
I
V
N
D
L
L
V
P
C
S
P
G
D
Q
Honey Bee
Apis mellifera
XP_393250
441
49311
T379
I
I
V
D
D
L
L
T
P
C
S
P
G
D
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
N448
Y
S
G
A
D
I
T
N
V
C
R
D
A
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
R457
D
D
L
T
N
V
C
R
D
A
S
M
N
G
M
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
C376
E
T
R
K
L
T
P
C
S
P
G
D
D
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
84.5
98.8
N.A.
99
36.4
N.A.
83.2
37.4
37.2
35.4
N.A.
74.2
77
N.A.
34.5
Protein Similarity:
100
85.3
84.6
99.7
N.A.
100
55.5
N.A.
87.1
54.2
55.7
56.7
N.A.
85.9
88.8
N.A.
52.3
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
13.3
N.A.
86.6
13.3
13.3
13.3
N.A.
60
80
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
20
20
20
N.A.
80
100
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
0
0
0
0
0
7
0
0
34
0
7
% A
% Cys:
0
0
0
0
0
0
7
7
0
87
0
0
0
0
0
% C
% Asp:
7
7
0
47
87
0
0
0
7
0
0
40
7
54
0
% D
% Glu:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
34
0
0
0
0
0
0
0
7
0
54
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
14
20
40
0
0
34
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
7
0
7
54
54
0
0
0
0
0
0
0
20
% L
% Met:
14
34
0
0
0
0
0
0
0
0
0
7
0
0
20
% M
% Asn:
0
0
0
7
7
0
0
34
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
54
7
0
54
0
0
47
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
0
0
7
0
0
0
0
7
0
0
34
0
0
0
0
% R
% Ser:
0
34
0
0
0
0
0
0
7
0
60
0
0
34
0
% S
% Thr:
0
7
0
7
0
7
34
47
0
0
0
0
0
0
0
% T
% Val:
20
0
14
0
0
7
0
7
27
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _