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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4A
All Species:
37.58
Human Site:
Y175
Identified Species:
59.05
UniProt:
Q9UN37
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN37
NP_037377.1
437
48898
Y175
P
P
G
T
G
K
S
Y
L
A
K
A
V
A
T
Chimpanzee
Pan troglodytes
XP_001147558
511
57412
Y249
P
P
G
T
G
K
S
Y
L
A
K
A
V
A
T
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
Y254
P
P
G
T
G
K
S
Y
L
A
K
A
V
A
T
Dog
Lupus familis
XP_536805
437
48918
Y175
P
P
G
T
G
K
S
Y
L
A
K
A
V
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ9
437
48888
Y175
P
P
G
T
G
K
S
Y
L
A
K
A
V
A
T
Rat
Rattus norvegicus
Q5XIK7
488
55183
A191
Y
D
K
D
L
V
E
A
L
E
R
D
I
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
Y222
P
P
G
T
G
K
S
Y
L
A
K
A
V
A
T
Chicken
Gallus gallus
Q1HGK7
492
56020
N162
R
E
K
K
D
Q
Q
N
K
G
K
E
E
K
S
Frog
Xenopus laevis
Q9PUL2
486
55412
A191
Y
D
K
D
L
I
E
A
L
E
R
D
I
I
S
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
Y184
K
K
F
D
G
T
G
Y
D
S
D
L
V
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573258
442
49577
Y180
P
P
G
T
G
K
S
Y
L
A
K
A
V
A
T
Honey Bee
Apis mellifera
XP_393250
441
49311
Y179
P
P
G
T
G
K
S
Y
L
A
K
A
V
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
N219
Y
D
K
D
L
V
E
N
L
E
R
D
I
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
G179
A
T
S
K
S
T
A
G
A
R
S
S
T
A
G
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
Y181
P
P
G
T
G
K
S
Y
L
A
K
A
V
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
84.5
98.8
N.A.
99
36.4
N.A.
83.2
37.4
37.2
35.4
N.A.
74.2
77
N.A.
34.5
Protein Similarity:
100
85.3
84.6
99.7
N.A.
100
55.5
N.A.
87.1
54.2
55.7
56.7
N.A.
85.9
88.8
N.A.
52.3
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
6.6
6.6
20
N.A.
100
100
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
100
20
26.6
26.6
N.A.
100
100
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
100
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
14
7
60
0
60
0
67
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
27
7
0
0
0
7
0
7
20
0
7
0
% D
% Glu:
0
7
0
0
0
0
20
0
0
20
0
7
7
0
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
60
0
67
0
7
7
0
7
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
0
0
20
7
0
% I
% Lys:
7
7
27
14
0
60
0
0
7
0
67
0
0
7
0
% K
% Leu:
0
0
0
0
20
0
0
0
80
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% N
% Pro:
60
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
7
% Q
% Arg:
7
0
0
0
0
0
0
0
0
7
20
0
0
0
0
% R
% Ser:
0
0
7
0
7
0
60
0
0
7
7
7
0
0
20
% S
% Thr:
0
7
0
60
0
14
0
0
0
0
0
0
7
0
60
% T
% Val:
0
0
0
0
0
14
0
0
0
0
0
0
67
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _