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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS4A All Species: 30.91
Human Site: Y329 Identified Species: 48.57
UniProt: Q9UN37 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UN37 NP_037377.1 437 48898 Y329 L A R K T E G Y S G A D I S I
Chimpanzee Pan troglodytes XP_001147558 511 57412 Y403 L A R K T E G Y S G A D I S I
Rhesus Macaque Macaca mulatta XP_001093648 516 56751 Y408 L A R K T E G Y S G A D I S I
Dog Lupus familis XP_536805 437 48918 Y329 L A R K T E G Y S G A D I S I
Cat Felis silvestris
Mouse Mus musculus Q8VEJ9 437 48888 Y329 L A R K T E G Y S G A D I S I
Rat Rattus norvegicus Q5XIK7 488 55183 I374 R R R L E K R I Y I P L P T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510255 484 54482 Y376 L A R R T E G Y S G A D I S I
Chicken Gallus gallus Q1HGK7 492 56020 I378 R R R L E K R I Y I P L P S A
Frog Xenopus laevis Q9PUL2 486 55412 I374 R R R L E K R I Y I P L P S A
Zebra Danio Brachydanio rerio Q5U3S1 488 54873 I374 R R R L E K R I Y I P L P T A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573258 442 49577 Y334 L A G K T E G Y S G A D I S I
Honey Bee Apis mellifera XP_393250 441 49311 Y333 L A A A T D G Y S G A D I S I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus O61577 516 57575 I402 R R R L E K R I Y I P L P E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 P411 L E K R I Y I P L P D F E S R
Baker's Yeast Sacchar. cerevisiae P52917 437 48154 M330 D Y R T L G A M T E G Y S G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.1 84.5 98.8 N.A. 99 36.4 N.A. 83.2 37.4 37.2 35.4 N.A. 74.2 77 N.A. 34.5
Protein Similarity: 100 85.3 84.6 99.7 N.A. 100 55.5 N.A. 87.1 54.2 55.7 56.7 N.A. 85.9 88.8 N.A. 52.3
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 93.3 13.3 13.3 6.6 N.A. 93.3 80 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 100 20 20 20 N.A. 93.3 86.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 36.5 60.8 N.A.
Protein Similarity: N.A. N.A. N.A. 54.6 76.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 54 7 7 0 0 7 0 0 0 54 0 0 0 27 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 7 0 0 0 0 7 54 0 0 0 % D
% Glu: 0 7 0 0 34 47 0 0 0 7 0 0 7 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 7 0 0 7 54 0 0 54 7 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 7 34 0 34 0 0 54 0 60 % I
% Lys: 0 0 7 40 0 34 0 0 0 0 0 0 0 0 0 % K
% Leu: 60 0 0 34 7 0 0 0 7 0 0 34 0 0 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 0 7 34 0 34 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 34 34 80 14 0 0 34 0 0 0 0 0 0 0 7 % R
% Ser: 0 0 0 0 0 0 0 0 54 0 0 0 7 74 7 % S
% Thr: 0 0 0 7 54 0 0 0 7 0 0 0 0 14 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 7 0 54 34 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _