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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS4A
All Species:
32.42
Human Site:
Y45
Identified Species:
50.95
UniProt:
Q9UN37
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN37
NP_037377.1
437
48898
Y45
Y
F
L
H
A
I
K
Y
E
A
H
S
D
K
A
Chimpanzee
Pan troglodytes
XP_001147558
511
57412
Y119
Y
F
L
H
A
I
K
Y
E
A
H
S
D
K
A
Rhesus Macaque
Macaca mulatta
XP_001093648
516
56751
Y124
Y
F
L
H
A
I
K
Y
E
A
H
S
D
K
A
Dog
Lupus familis
XP_536805
437
48918
Y45
Y
F
L
H
A
I
K
Y
E
A
H
S
D
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ9
437
48888
Y45
Y
F
L
H
A
I
K
Y
E
A
H
S
D
K
A
Rat
Rattus norvegicus
Q5XIK7
488
55183
Q53
P
A
T
K
A
K
W
Q
Q
V
R
Q
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510255
484
54482
Y92
Y
F
L
H
A
I
K
Y
E
A
H
S
D
K
A
Chicken
Gallus gallus
Q1HGK7
492
56020
D45
K
Y
L
Y
S
L
R
D
T
Y
L
Q
Q
K
W
Frog
Xenopus laevis
Q9PUL2
486
55412
D45
K
Y
L
Y
S
V
K
D
T
F
L
Q
Q
K
W
Zebra Danio
Brachydanio rerio
Q5U3S1
488
54873
Q53
P
A
Q
K
V
K
W
Q
Q
V
R
Q
E
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573258
442
49577
Y46
Y
F
L
H
T
I
K
Y
E
A
Q
G
E
K
A
Honey Bee
Apis mellifera
XP_393250
441
49311
Y46
Y
F
L
H
S
I
K
Y
E
A
Q
G
D
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
O61577
516
57575
S78
K
T
L
N
G
F
K
S
E
P
A
A
P
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SEX2
523
57218
T47
Q
I
N
K
H
L
N
T
L
D
D
P
L
A
R
Baker's Yeast
Sacchar. cerevisiae
P52917
437
48154
K45
D
Y
L
M
L
A
L
K
Y
E
K
N
P
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
84.5
98.8
N.A.
99
36.4
N.A.
83.2
37.4
37.2
35.4
N.A.
74.2
77
N.A.
34.5
Protein Similarity:
100
85.3
84.6
99.7
N.A.
100
55.5
N.A.
87.1
54.2
55.7
56.7
N.A.
85.9
88.8
N.A.
52.3
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
13.3
20
6.6
N.A.
73.3
73.3
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
46.6
46.6
20
N.A.
80
86.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
60.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.6
76.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
47
7
0
0
0
54
7
7
0
7
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
14
0
7
7
0
47
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
60
7
0
0
20
7
0
% E
% Phe:
0
54
0
0
0
7
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
14
0
0
0
% G
% His:
0
0
0
54
7
0
0
0
0
0
40
0
0
0
0
% H
% Ile:
0
7
0
0
0
54
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
0
20
0
14
67
7
0
0
7
0
0
67
0
% K
% Leu:
0
0
80
0
7
14
7
0
7
0
14
0
7
14
7
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
0
7
0
0
0
0
7
0
0
0
% N
% Pro:
14
0
0
0
0
0
0
0
0
7
0
7
14
0
7
% P
% Gln:
7
0
7
0
0
0
0
14
14
0
14
27
14
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
14
0
0
7
7
% R
% Ser:
0
0
0
0
20
0
0
7
0
0
0
40
0
0
7
% S
% Thr:
0
7
7
0
7
0
0
7
14
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
7
0
0
0
14
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
14
% W
% Tyr:
54
20
0
14
0
0
0
54
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _