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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP1B4
All Species:
22.73
Human Site:
S281
Identified Species:
55.56
UniProt:
Q9UN42
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UN42
NP_001135919.1
357
41598
S281
G
D
E
N
D
I
R
S
I
S
Y
Y
P
E
S
Chimpanzee
Pan troglodytes
XP_001139236
403
46039
S327
G
D
E
N
D
I
R
S
I
S
Y
Y
P
E
S
Rhesus Macaque
Macaca mulatta
XP_001085973
353
41132
S277
G
D
E
N
D
I
R
S
I
S
Y
Y
P
E
S
Dog
Lupus familis
XP_538158
362
42111
S286
G
D
E
N
D
I
R
S
I
N
Y
Y
P
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99ME6
356
41382
S280
G
D
E
N
D
I
R
S
I
N
Y
Y
P
E
S
Rat
Rattus norvegicus
Q9R193
356
41499
S280
G
D
E
N
D
I
R
S
I
N
Y
Y
P
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510069
325
36818
K269
M
Y
Y
P
Y
Y
G
K
L
T
H
V
N
Y
T
Chicken
Gallus gallus
Q2HZ96
321
36344
K265
M
Y
Y
P
Y
Y
G
K
L
T
H
V
N
Y
T
Frog
Xenopus laevis
Q202B1
314
36111
K259
M
Y
Y
P
Y
Y
G
K
L
T
H
V
N
Y
T
Zebra Danio
Brachydanio rerio
XP_002664470
410
46393
G334
K
G
S
T
E
V
L
G
E
V
K
F
F
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
97.4
91.7
N.A.
89
89
N.A.
55.4
51.2
45.9
38.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
87
98.5
94.7
N.A.
95.5
94.9
N.A.
68.3
65.8
64.9
54.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
0
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
26.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
60
0
0
60
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
60
0
10
0
0
0
10
0
0
0
0
60
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% F
% Gly:
60
10
0
0
0
0
30
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
30
0
0
0
0
% H
% Ile:
0
0
0
0
0
60
0
0
60
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
30
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
30
0
0
0
0
0
0
% L
% Met:
30
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
60
0
0
0
0
0
30
0
0
30
0
10
% N
% Pro:
0
0
0
30
0
0
0
0
0
0
0
0
60
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
60
0
30
0
0
0
0
60
% S
% Thr:
0
0
0
10
0
0
0
0
0
30
0
0
0
0
30
% T
% Val:
0
0
0
0
0
10
0
0
0
10
0
30
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
30
30
0
30
30
0
0
0
0
60
60
0
30
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _