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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS5
All Species:
20.3
Human Site:
Y790
Identified Species:
49.63
UniProt:
Q9UNA0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNA0
NP_008969
930
101716
Y790
E
Y
L
I
N
G
K
Y
M
I
S
T
S
E
T
Chimpanzee
Pan troglodytes
XP_531407
930
101735
Y790
E
Y
L
I
N
G
K
Y
M
I
S
T
S
E
T
Rhesus Macaque
Macaca mulatta
XP_001103439
930
101678
Y790
E
Y
L
I
N
G
K
Y
M
I
S
T
S
E
T
Dog
Lupus familis
XP_851118
800
88142
S665
G
K
Y
M
I
S
T
S
E
T
I
I
D
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9R001
930
101762
Y790
E
Y
L
I
N
G
K
Y
M
I
S
T
S
E
T
Rat
Rattus norvegicus
Q9WUQ1
967
105687
F783
T
Y
I
L
N
G
N
F
T
L
S
T
L
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520667
420
45768
L285
R
K
S
G
E
Y
L
L
N
G
G
Y
V
I
S
Chicken
Gallus gallus
XP_425541
750
82814
E615
K
Y
M
I
S
T
S
E
T
I
I
D
I
N
G
Frog
Xenopus laevis
NP_001088627
928
102191
Y733
T
Y
I
L
N
G
D
Y
T
L
S
T
L
E
Q
Zebra Danio
Brachydanio rerio
NP_001119901
958
105214
Y734
K
Y
L
L
N
G
N
Y
V
V
S
A
M
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.7
80.8
N.A.
90.1
39.5
N.A.
38.1
69.8
42.7
39.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
97.9
82
N.A.
92.3
53.8
N.A.
42.3
74.7
56.8
54.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
40
N.A.
0
20
46.6
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
66.6
N.A.
6.6
40
66.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
10
10
0
0
% D
% Glu:
40
0
0
0
10
0
0
10
10
0
0
0
0
70
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
70
0
0
0
10
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
20
50
10
0
0
0
0
50
20
10
10
20
0
% I
% Lys:
20
20
0
0
0
0
40
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
50
30
0
0
10
10
0
20
0
0
20
0
0
% L
% Met:
0
0
10
10
0
0
0
0
40
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
70
0
20
0
10
0
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
10
10
10
0
0
70
0
40
0
10
% S
% Thr:
20
0
0
0
0
10
10
0
30
10
0
60
0
0
40
% T
% Val:
0
0
0
0
0
0
0
0
10
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
80
10
0
0
10
0
60
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _