KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EDAR
All Species:
28.79
Human Site:
S274
Identified Species:
70.37
UniProt:
Q9UNE0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNE0
NP_071731.1
448
48582
S274
K
S
E
N
D
A
S
S
E
N
E
Q
L
L
S
Chimpanzee
Pan troglodytes
XP_001139513
480
51637
S306
K
S
E
N
D
A
S
S
E
N
E
Q
L
L
S
Rhesus Macaque
Macaca mulatta
XP_001084259
448
48620
S274
K
S
E
N
D
A
S
S
E
N
E
Q
L
L
S
Dog
Lupus familis
XP_538426
459
50038
S285
A
K
S
E
N
D
A
S
S
E
N
E
Q
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R187
448
48416
S274
K
S
E
N
D
A
S
S
E
N
E
Q
L
L
S
Rat
Rattus norvegicus
XP_001053577
529
57454
S355
K
S
E
N
D
A
S
S
E
N
E
Q
L
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515681
299
32356
E127
S
E
N
D
A
S
S
E
N
E
Q
L
L
S
R
Chicken
Gallus gallus
NP_001012629
448
49289
S275
K
S
E
N
D
A
S
S
E
N
E
R
L
L
S
Frog
Xenopus laevis
NP_001080516
453
49933
S273
K
N
E
N
D
A
S
S
E
N
E
R
L
L
S
Zebra Danio
Brachydanio rerio
NP_001108536
459
50200
I283
E
Q
L
L
S
R
S
I
D
S
D
E
E
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
99.3
90.6
N.A.
91.5
77.1
N.A.
58.2
84.8
77
66
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.3
99.3
93
N.A.
93.9
79.2
N.A.
61.6
90.8
86.3
77.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
13.3
93.3
86.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
33.3
100
100
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
70
10
0
0
0
0
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
70
10
0
0
10
0
10
0
0
0
0
% D
% Glu:
10
10
70
10
0
0
0
10
70
20
70
20
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
70
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
10
0
0
0
0
0
0
0
10
80
80
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
70
10
0
0
0
10
70
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
10
50
10
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
20
0
0
10
% R
% Ser:
10
60
10
0
10
10
90
80
10
10
0
0
0
10
70
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _