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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC14A
All Species:
19.39
Human Site:
S468
Identified Species:
47.41
UniProt:
Q9UNH5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNH5
NP_003663.2
594
66574
S468
I
N
R
T
S
L
S
S
G
A
T
V
R
S
F
Chimpanzee
Pan troglodytes
XP_001135275
594
66545
S468
I
N
R
T
S
L
S
S
G
A
T
V
R
S
F
Rhesus Macaque
Macaca mulatta
XP_001107228
596
66950
S470
I
N
R
T
S
L
S
S
G
A
T
V
R
S
F
Dog
Lupus familis
XP_852997
625
69905
S470
I
N
R
S
S
L
S
S
G
A
S
V
R
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6GQT0
603
67616
S468
I
S
R
G
S
L
S
S
G
A
N
I
R
S
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520276
518
58161
D393
N
L
H
A
A
S
D
D
S
E
S
K
K
T
S
Chicken
Gallus gallus
NP_001171207
603
67885
E477
A
V
N
S
S
S
A
E
R
I
N
R
I
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P81299
1063
120230
N522
L
K
T
T
P
N
G
N
V
A
Y
R
T
R
N
Sea Urchin
Strong. purpuratus
XP_781590
534
60264
T409
S
R
K
A
R
S
A
T
T
G
S
L
K
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00684
551
61888
P426
S
F
K
S
S
A
V
P
Q
T
S
P
G
Q
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.6
87.8
N.A.
87
N.A.
N.A.
61.9
70.3
N.A.
N.A.
N.A.
N.A.
N.A.
27
53
Protein Similarity:
100
99.4
96.4
91.3
N.A.
91.8
N.A.
N.A.
71.2
81.4
N.A.
N.A.
N.A.
N.A.
N.A.
38.8
67.8
P-Site Identity:
100
100
100
86.6
N.A.
73.3
N.A.
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
20
10
10
20
0
0
60
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
50
% F
% Gly:
0
0
0
10
0
0
10
0
50
10
0
0
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% I
% Lys:
0
10
20
0
0
0
0
0
0
0
0
10
20
0
0
% K
% Leu:
10
10
0
0
0
50
0
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
40
10
0
0
10
0
10
0
0
20
0
0
0
10
% N
% Pro:
0
0
0
0
10
0
0
10
0
0
0
10
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
10
50
0
10
0
0
0
10
0
0
20
50
10
0
% R
% Ser:
20
10
0
30
70
30
50
50
10
0
40
0
0
50
20
% S
% Thr:
0
0
10
40
0
0
0
10
10
10
30
0
10
20
0
% T
% Val:
0
10
0
0
0
0
10
0
10
0
0
40
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _