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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDC14A All Species: 21.82
Human Site: S483 Identified Species: 53.33
UniProt: Q9UNH5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNH5 NP_003663.2 594 66574 S483 S I N S R L A S S L G N L N A
Chimpanzee Pan troglodytes XP_001135275 594 66545 S483 S I N S R L A S S L G N L N A
Rhesus Macaque Macaca mulatta XP_001107228 596 66950 S485 S I N S R L A S S L G N L N A
Dog Lupus familis XP_852997 625 69905 S485 S I N S R L A S S L G N L N A
Cat Felis silvestris
Mouse Mus musculus Q6GQT0 603 67616 S483 S I N S R L A S S L G N L N A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520276 518 58161 P408 A P C R T V Y P V N H I S S H
Chicken Gallus gallus NP_001171207 603 67885 S492 S S G S N L K S I S I N S R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P81299 1063 120230 T537 S S G N T T S T L T R T P A S
Sea Urchin Strong. purpuratus XP_781590 534 60264 S424 E G K I H T R S T S S Q P L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00684 551 61888 N441 R K G Q N G S N T I E D I N N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.6 87.8 N.A. 87 N.A. N.A. 61.9 70.3 N.A. N.A. N.A. N.A. N.A. 27 53
Protein Similarity: 100 99.4 96.4 91.3 N.A. 91.8 N.A. N.A. 71.2 81.4 N.A. N.A. N.A. N.A. N.A. 38.8 67.8
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 0 33.3 N.A. N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 20 33.3 N.A. N.A. N.A. N.A. N.A. 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 50 0 0 0 0 0 0 10 50 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 30 0 0 10 0 0 0 0 50 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 10 % H
% Ile: 0 50 0 10 0 0 0 0 10 10 10 10 10 0 0 % I
% Lys: 0 10 10 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 60 0 0 10 50 0 0 50 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 50 10 20 0 0 10 0 10 0 60 0 60 10 % N
% Pro: 0 10 0 0 0 0 0 10 0 0 0 0 20 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 10 0 0 10 50 0 10 0 0 0 10 0 0 10 10 % R
% Ser: 70 20 0 60 0 0 20 70 50 20 10 0 20 10 10 % S
% Thr: 0 0 0 0 20 20 0 10 20 10 0 10 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _