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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC14A
All Species:
22.42
Human Site:
S75
Identified Species:
54.81
UniProt:
Q9UNH5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNH5
NP_003663.2
594
66574
S75
N
K
K
L
K
S
Y
S
L
S
R
K
K
I
V
Chimpanzee
Pan troglodytes
XP_001135275
594
66545
S75
N
K
K
L
K
S
Y
S
L
S
R
K
K
I
V
Rhesus Macaque
Macaca mulatta
XP_001107228
596
66950
S76
N
K
K
L
K
S
Y
S
L
S
R
K
K
I
V
Dog
Lupus familis
XP_852997
625
69905
S75
N
K
K
L
K
S
Y
S
L
S
R
K
K
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6GQT0
603
67616
S75
N
K
K
L
K
S
Y
S
L
S
R
K
K
I
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520276
518
58161
P21
A
L
L
S
G
S
N
P
P
Y
L
P
F
R
D
Chicken
Gallus gallus
NP_001171207
603
67885
S92
N
K
K
L
K
Y
F
S
L
S
R
K
K
I
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P81299
1063
120230
E87
G
K
L
L
E
V
E
E
K
R
S
R
R
V
V
Sea Urchin
Strong. purpuratus
XP_781590
534
60264
F36
S
T
T
N
T
H
Y
F
C
I
D
D
E
F
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00684
551
61888
M54
F
H
L
D
F
G
P
M
N
I
G
H
L
Y
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.6
87.8
N.A.
87
N.A.
N.A.
61.9
70.3
N.A.
N.A.
N.A.
N.A.
N.A.
27
53
Protein Similarity:
100
99.4
96.4
91.3
N.A.
91.8
N.A.
N.A.
71.2
81.4
N.A.
N.A.
N.A.
N.A.
N.A.
38.8
67.8
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
10
10
0
0
10
% D
% Glu:
0
0
0
0
10
0
10
10
0
0
0
0
10
0
0
% E
% Phe:
10
0
0
0
10
0
10
10
0
0
0
0
10
10
0
% F
% Gly:
10
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
20
0
0
0
60
0
% I
% Lys:
0
70
60
0
60
0
0
0
10
0
0
60
60
0
0
% K
% Leu:
0
10
30
70
0
0
0
0
60
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
60
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
10
10
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
60
10
10
10
10
% R
% Ser:
10
0
0
10
0
60
0
60
0
60
10
0
0
0
0
% S
% Thr:
0
10
10
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
60
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _