KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC14A
All Species:
15.76
Human Site:
T447
Identified Species:
38.52
UniProt:
Q9UNH5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNH5
NP_003663.2
594
66574
T447
G
S
A
V
T
L
K
T
S
K
M
A
L
S
P
Chimpanzee
Pan troglodytes
XP_001135275
594
66545
T447
G
S
A
V
T
L
K
T
S
K
M
A
L
S
P
Rhesus Macaque
Macaca mulatta
XP_001107228
596
66950
T449
G
S
A
P
T
L
K
T
S
K
M
A
L
S
S
Dog
Lupus familis
XP_852997
625
69905
T449
G
S
V
S
T
L
K
T
S
K
V
A
L
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6GQT0
603
67616
T447
P
T
M
S
T
M
K
T
S
K
V
C
L
S
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520276
518
58161
K372
A
T
S
N
A
N
T
K
S
F
S
I
H
S
R
Chicken
Gallus gallus
NP_001171207
603
67885
M456
R
L
N
T
S
G
T
M
E
G
S
V
S
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P81299
1063
120230
P501
R
E
P
I
I
V
T
P
S
K
N
G
T
S
S
Sea Urchin
Strong. purpuratus
XP_781590
534
60264
Q388
R
S
T
L
S
G
S
Q
A
M
T
Q
G
D
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00684
551
61888
R405
G
H
G
A
L
S
A
R
N
S
S
Q
P
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.6
87.8
N.A.
87
N.A.
N.A.
61.9
70.3
N.A.
N.A.
N.A.
N.A.
N.A.
27
53
Protein Similarity:
100
99.4
96.4
91.3
N.A.
91.8
N.A.
N.A.
71.2
81.4
N.A.
N.A.
N.A.
N.A.
N.A.
38.8
67.8
P-Site Identity:
100
100
86.6
80
N.A.
53.3
N.A.
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
86.6
86.6
N.A.
73.3
N.A.
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
30
10
10
0
10
0
10
0
0
40
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
50
0
10
0
0
20
0
0
0
10
0
10
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
50
10
0
60
0
0
0
0
10
% K
% Leu:
0
10
0
10
10
40
0
0
0
0
0
0
50
0
10
% L
% Met:
0
0
10
0
0
10
0
10
0
10
30
0
0
0
0
% M
% Asn:
0
0
10
10
0
10
0
0
10
0
10
0
0
0
0
% N
% Pro:
10
0
10
10
0
0
0
10
0
0
0
0
10
10
40
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
20
0
0
0
% Q
% Arg:
30
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
0
50
10
20
20
10
10
0
70
10
30
0
10
80
20
% S
% Thr:
0
20
10
10
50
0
30
50
0
0
10
0
10
0
10
% T
% Val:
0
0
10
20
0
10
0
0
0
0
20
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _