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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC14A
All Species:
26.36
Human Site:
Y169
Identified Species:
64.44
UniProt:
Q9UNH5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNH5
NP_003663.2
594
66574
Y169
E
T
F
D
V
D
E
Y
E
H
Y
E
R
V
E
Chimpanzee
Pan troglodytes
XP_001135275
594
66545
Y169
E
T
F
D
V
D
E
Y
E
H
Y
E
R
V
E
Rhesus Macaque
Macaca mulatta
XP_001107228
596
66950
Y170
E
T
F
D
V
D
E
Y
E
H
Y
E
R
V
E
Dog
Lupus familis
XP_852997
625
69905
Y169
E
T
F
D
V
D
E
Y
E
H
Y
E
R
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6GQT0
603
67616
Y169
E
T
F
D
A
E
E
Y
E
H
Y
E
R
V
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520276
518
58161
E107
G
Y
P
L
H
A
P
E
A
Y
F
P
Y
F
R
Chicken
Gallus gallus
NP_001171207
603
67885
Y186
K
T
F
D
V
D
E
Y
E
H
Y
E
R
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P81299
1063
120230
Y186
S
D
F
D
Y
E
E
Y
E
F
Y
E
R
V
E
Sea Urchin
Strong. purpuratus
XP_781590
534
60264
A122
I
S
I
Y
F
V
T
A
D
N
L
S
I
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00684
551
61888
T140
S
N
A
D
F
E
I
T
I
Q
D
V
V
Y
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.6
87.8
N.A.
87
N.A.
N.A.
61.9
70.3
N.A.
N.A.
N.A.
N.A.
N.A.
27
53
Protein Similarity:
100
99.4
96.4
91.3
N.A.
91.8
N.A.
N.A.
71.2
81.4
N.A.
N.A.
N.A.
N.A.
N.A.
38.8
67.8
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
0
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
13.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
10
0
10
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
80
0
50
0
0
10
0
10
0
0
0
10
% D
% Glu:
50
0
0
0
0
30
70
10
70
0
0
70
0
0
70
% E
% Phe:
0
0
70
0
20
0
0
0
0
10
10
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
10
0
0
0
0
60
0
0
0
0
0
% H
% Ile:
10
0
10
0
0
0
10
0
10
0
0
0
10
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
10
% R
% Ser:
20
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
60
0
0
0
0
10
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
50
10
0
0
0
0
0
10
10
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
10
0
0
70
0
10
70
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _