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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP12 All Species: 24.85
Human Site: S210 Identified Species: 39.05
UniProt: Q9UNI6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNI6 NP_009171.1 340 37687 S210 A V D P T T V S Q G L K D E V
Chimpanzee Pan troglodytes XP_514446 364 39904 S234 A V D P T T V S Q G L K D E V
Rhesus Macaque Macaca mulatta XP_001118147 340 37885 S210 A V D P T T V S Q G L K D E V
Dog Lupus familis XP_536142 339 37199 S209 A V D P T T I S Q G L K D G I
Cat Felis silvestris
Mouse Mus musculus Q9D0T2 339 37140 S209 A V D P T T I S Q G L K D D I
Rat Rattus norvegicus Q9JIM4 339 37178 S209 A V D P T T V S Q G L K D D I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423122 309 33303 C179 A V D P T I A C Q T P N T E V
Frog Xenopus laevis Q6GQJ8 209 23467 H87 K G E G C L V H C L A G V S R
Zebra Danio Brachydanio rerio Q566R7 183 20613 Q61 A A A D S P T Q N L I Q H F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608332 387 43724 T223 V R P D P D I T R E N P E P I
Honey Bee Apis mellifera XP_396430 347 39479 A206 I K P D P A L A T V H P E P T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203068 264 29514 F142 F M E Q L K L F E A M G C Q C
Poplar Tree Populus trichocarpa XP_002308890 352 39035 Q223 A D P G V P T Q V S S E E E A
Maize Zea mays NP_001130071 354 39026 L227 E D D P G L S L E S G S C Q D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02256 364 41167 S225 K L T E A E K S K V T A V R C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 96.1 85.2 N.A. 83.5 82.6 N.A. N.A. 58.5 20.8 21.7 N.A. 31.7 31.9 N.A. 26.4
Protein Similarity: 100 93.4 96.4 89.1 N.A. 89.7 89.1 N.A. N.A. 70.5 36.1 33.5 N.A. 48.5 49.8 N.A. 43.8
P-Site Identity: 100 100 100 80 N.A. 80 86.6 N.A. N.A. 53.3 6.6 6.6 N.A. 0 0 N.A. 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 53.3 13.3 26.6 N.A. 33.3 20 N.A. 40
Percent
Protein Identity: 37.2 34.7 N.A. N.A. 26.6 N.A.
Protein Similarity: 55.4 51.9 N.A. N.A. 46.9 N.A.
P-Site Identity: 13.3 13.3 N.A. N.A. 6.6 N.A.
P-Site Similarity: 26.6 26.6 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 60 7 7 0 7 7 7 7 0 7 7 7 0 0 7 % A
% Cys: 0 0 0 0 7 0 0 7 7 0 0 0 14 0 14 % C
% Asp: 0 14 54 20 0 7 0 0 0 0 0 0 40 14 7 % D
% Glu: 7 0 14 7 0 7 0 0 14 7 0 7 20 34 0 % E
% Phe: 7 0 0 0 0 0 0 7 0 0 0 0 0 7 0 % F
% Gly: 0 7 0 14 7 0 0 0 0 40 7 14 0 7 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 7 0 7 0 0 % H
% Ile: 7 0 0 0 0 7 20 0 0 0 7 0 0 0 27 % I
% Lys: 14 7 0 0 0 7 7 0 7 0 0 40 0 0 0 % K
% Leu: 0 7 0 0 7 14 14 7 0 14 40 0 0 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 7 7 0 0 0 % N
% Pro: 0 0 20 54 14 14 0 0 0 0 7 14 0 14 0 % P
% Gln: 0 0 0 7 0 0 0 14 47 0 0 7 0 14 0 % Q
% Arg: 0 7 0 0 0 0 0 0 7 0 0 0 0 7 14 % R
% Ser: 0 0 0 0 7 0 7 47 0 14 7 7 0 7 0 % S
% Thr: 0 0 7 0 47 40 14 7 7 7 7 0 7 0 7 % T
% Val: 7 47 0 0 7 0 34 0 7 14 0 0 14 0 27 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _