Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP12 All Species: 17.58
Human Site: S22 Identified Species: 27.62
UniProt: Q9UNI6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNI6 NP_009171.1 340 37687 S22 N P S A S R V S C A G Q M L E
Chimpanzee Pan troglodytes XP_514446 364 39904 S35 N P S A S R V S C A G Q M L E
Rhesus Macaque Macaca mulatta XP_001118147 340 37885 T22 N P S A S R A T C A G Q M L E
Dog Lupus familis XP_536142 339 37199 R22 S A G G R A G R A G H L L E V
Cat Felis silvestris
Mouse Mus musculus Q9D0T2 339 37140 S22 A P T A S P A S S A G H A V E
Rat Rattus norvegicus Q9JIM4 339 37178 S22 A P T T S P A S S A G H A V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423122 309 33303 L22 S C S S S K A L A A A G V M A
Frog Xenopus laevis Q6GQJ8 209 23467
Zebra Danio Brachydanio rerio Q566R7 183 20613
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608332 387 43724 Q22 S A G G G K A Q D S G V L T R
Honey Bee Apis mellifera XP_396430 347 39479 D22 D A G P S S Y D E I I P S L F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203068 264 29514
Poplar Tree Populus trichocarpa XP_002308890 352 39035 T29 Q N G S A E I T H I L S V L S
Maize Zea mays NP_001130071 354 39026 T22 K D A I A A L T E S S S T P D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02256 364 41167 G22 I L G G I Y L G G I R P I I D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 96.1 85.2 N.A. 83.5 82.6 N.A. N.A. 58.5 20.8 21.7 N.A. 31.7 31.9 N.A. 26.4
Protein Similarity: 100 93.4 96.4 89.1 N.A. 89.7 89.1 N.A. N.A. 70.5 36.1 33.5 N.A. 48.5 49.8 N.A. 43.8
P-Site Identity: 100 100 86.6 0 N.A. 46.6 40 N.A. N.A. 20 0 0 N.A. 6.6 13.3 N.A. 0
P-Site Similarity: 100 100 93.3 13.3 N.A. 60 53.3 N.A. N.A. 53.3 0 0 N.A. 33.3 20 N.A. 0
Percent
Protein Identity: 37.2 34.7 N.A. N.A. 26.6 N.A.
Protein Similarity: 55.4 51.9 N.A. N.A. 46.9 N.A.
P-Site Identity: 6.6 0 N.A. N.A. 0 N.A.
P-Site Similarity: 40 40 N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 20 7 27 14 14 34 0 14 40 7 0 14 0 7 % A
% Cys: 0 7 0 0 0 0 0 0 20 0 0 0 0 0 0 % C
% Asp: 7 7 0 0 0 0 0 7 7 0 0 0 0 0 14 % D
% Glu: 0 0 0 0 0 7 0 0 14 0 0 0 0 7 34 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 34 20 7 0 7 7 7 7 40 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 7 14 0 0 0 % H
% Ile: 7 0 0 7 7 0 7 0 0 20 7 0 7 7 0 % I
% Lys: 7 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 7 0 0 0 0 14 7 0 0 7 7 14 34 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 20 7 0 % M
% Asn: 20 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 34 0 7 0 14 0 0 0 0 0 14 0 7 0 % P
% Gln: 7 0 0 0 0 0 0 7 0 0 0 20 0 0 0 % Q
% Arg: 0 0 0 0 7 20 0 7 0 0 7 0 0 0 7 % R
% Ser: 20 0 27 14 47 7 0 27 14 14 7 14 7 0 7 % S
% Thr: 0 0 14 7 0 0 0 20 0 0 0 0 7 7 0 % T
% Val: 0 0 0 0 0 0 14 0 0 0 0 7 14 14 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _