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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP12
All Species:
23.03
Human Site:
S227
Identified Species:
36.19
UniProt:
Q9UNI6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNI6
NP_009171.1
340
37687
S227
K
C
R
K
C
R
R
S
L
F
R
S
S
S
I
Chimpanzee
Pan troglodytes
XP_514446
364
39904
S251
K
C
R
K
C
R
R
S
L
F
R
S
S
S
I
Rhesus Macaque
Macaca mulatta
XP_001118147
340
37885
S227
K
C
R
K
C
R
R
S
L
F
R
S
S
S
I
Dog
Lupus familis
XP_536142
339
37199
S226
K
C
R
K
C
R
R
S
L
F
R
S
S
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0T2
339
37140
S226
K
C
R
K
C
R
R
S
L
F
R
H
S
S
I
Rat
Rattus norvegicus
Q9JIM4
339
37178
S226
K
C
R
K
C
R
R
S
L
F
R
R
S
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423122
309
33303
A196
R
C
R
K
C
R
R
A
L
F
R
S
S
S
I
Frog
Xenopus laevis
Q6GQJ8
209
23467
M104
T
L
V
V
A
Y
V
M
T
V
T
D
F
G
W
Zebra Danio
Brachydanio rerio
Q566R7
183
20613
R78
I
A
F
I
H
Q
S
R
L
K
G
E
G
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608332
387
43724
V240
R
C
R
R
C
R
R
V
L
A
S
K
S
H
V
Honey Bee
Apis mellifera
XP_396430
347
39479
I223
R
C
K
K
C
R
R
I
V
A
S
A
S
N
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203068
264
29514
H159
T
N
S
Q
F
K
Q
H
R
L
S
H
L
A
E
Poplar Tree
Populus trichocarpa
XP_002308890
352
39035
P240
N
G
G
E
K
G
I
P
A
Y
H
C
K
K
C
Maize
Zea mays
NP_001130071
354
39026
A244
K
V
E
Q
R
K
T
A
Y
R
C
R
K
C
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02256
364
41167
S242
C
R
T
K
L
A
L
S
T
S
F
I
A
H
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
96.1
85.2
N.A.
83.5
82.6
N.A.
N.A.
58.5
20.8
21.7
N.A.
31.7
31.9
N.A.
26.4
Protein Similarity:
100
93.4
96.4
89.1
N.A.
89.7
89.1
N.A.
N.A.
70.5
36.1
33.5
N.A.
48.5
49.8
N.A.
43.8
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
0
6.6
N.A.
46.6
46.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
0
20
N.A.
66.6
80
N.A.
26.6
Percent
Protein Identity:
37.2
34.7
N.A.
N.A.
26.6
N.A.
Protein Similarity:
55.4
51.9
N.A.
N.A.
46.9
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
13.3
26.6
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
7
0
14
7
14
0
7
7
7
0
% A
% Cys:
7
60
0
0
60
0
0
0
0
0
7
7
0
14
7
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% D
% Glu:
0
0
7
7
0
0
0
0
0
0
0
7
0
0
7
% E
% Phe:
0
0
7
0
7
0
0
0
0
47
7
0
7
0
0
% F
% Gly:
0
7
7
0
0
7
0
0
0
0
7
0
7
7
0
% G
% His:
0
0
0
0
7
0
0
7
0
0
7
14
0
14
0
% H
% Ile:
7
0
0
7
0
0
7
7
0
0
0
7
0
0
54
% I
% Lys:
47
0
7
60
7
14
0
0
0
7
0
7
14
7
0
% K
% Leu:
0
7
0
0
7
0
7
0
60
7
0
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
14
0
7
7
0
0
0
0
0
0
0
0
% Q
% Arg:
20
7
54
7
7
60
60
7
7
7
47
14
0
0
7
% R
% Ser:
0
0
7
0
0
0
7
47
0
7
20
34
60
47
0
% S
% Thr:
14
0
7
0
0
0
7
0
14
0
7
0
0
0
0
% T
% Val:
0
7
7
7
0
0
7
7
7
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
7
0
0
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _