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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP12 All Species: 24.55
Human Site: S233 Identified Species: 38.57
UniProt: Q9UNI6 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNI6 NP_009171.1 340 37687 S233 R S L F R S S S I L D H R E G
Chimpanzee Pan troglodytes XP_514446 364 39904 S257 R S L F R S S S I L D H R E G
Rhesus Macaque Macaca mulatta XP_001118147 340 37885 S233 R S L F R S S S I L D H H E G
Dog Lupus familis XP_536142 339 37199 S232 R S L F R S S S I L D H N E G
Cat Felis silvestris
Mouse Mus musculus Q9D0T2 339 37140 S232 R S L F R H S S I L G H S E G
Rat Rattus norvegicus Q9JIM4 339 37178 S232 R S L F R R S S I L D H S E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423122 309 33303 S202 R A L F R S S S I L S H V E G
Frog Xenopus laevis Q6GQJ8 209 23467 G110 V M T V T D F G W E D S L S A
Zebra Danio Brachydanio rerio Q566R7 183 20613 C84 S R L K G E G C L V H C L A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608332 387 43724 H246 R V L A S K S H V L E H K P R
Honey Bee Apis mellifera XP_396430 347 39479 N229 R I V A S A S N I L P H M P K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203068 264 29514 A165 Q H R L S H L A E E I H S R E
Poplar Tree Populus trichocarpa XP_002308890 352 39035 K246 I P A Y H C K K C R R V V A L
Maize Zea mays NP_001130071 354 39026 C250 T A Y R C R K C R R V I A V E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02256 364 41167 H248 L S T S F I A H D P P S K E S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 96.1 85.2 N.A. 83.5 82.6 N.A. N.A. 58.5 20.8 21.7 N.A. 31.7 31.9 N.A. 26.4
Protein Similarity: 100 93.4 96.4 89.1 N.A. 89.7 89.1 N.A. N.A. 70.5 36.1 33.5 N.A. 48.5 49.8 N.A. 43.8
P-Site Identity: 100 100 93.3 93.3 N.A. 80 86.6 N.A. N.A. 80 6.6 13.3 N.A. 33.3 33.3 N.A. 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 80 86.6 N.A. N.A. 86.6 6.6 26.6 N.A. 53.3 53.3 N.A. 20
Percent
Protein Identity: 37.2 34.7 N.A. N.A. 26.6 N.A.
Protein Similarity: 55.4 51.9 N.A. N.A. 46.9 N.A.
P-Site Identity: 0 0 N.A. N.A. 13.3 N.A.
P-Site Similarity: 6.6 6.6 N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 7 14 0 7 7 7 0 0 0 0 7 14 7 % A
% Cys: 0 0 0 0 7 7 0 14 7 0 0 7 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 7 0 40 0 0 0 0 % D
% Glu: 0 0 0 0 0 7 0 0 7 14 7 0 0 54 14 % E
% Phe: 0 0 0 47 7 0 7 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 7 7 0 0 7 0 0 0 54 % G
% His: 0 7 0 0 7 14 0 14 0 0 7 67 7 0 0 % H
% Ile: 7 7 0 0 0 7 0 0 54 0 7 7 0 0 0 % I
% Lys: 0 0 0 7 0 7 14 7 0 0 0 0 14 0 7 % K
% Leu: 7 0 60 7 0 0 7 0 7 60 0 0 14 0 7 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 7 14 0 0 14 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 60 7 7 7 47 14 0 0 7 14 7 0 14 7 7 % R
% Ser: 7 47 0 7 20 34 60 47 0 0 7 14 20 7 7 % S
% Thr: 7 0 14 0 7 0 0 0 0 0 0 0 0 0 0 % T
% Val: 7 7 7 7 0 0 0 0 7 7 7 7 14 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _