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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP12
All Species:
25.76
Human Site:
S241
Identified Species:
40.48
UniProt:
Q9UNI6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNI6
NP_009171.1
340
37687
S241
I
L
D
H
R
E
G
S
G
P
I
A
F
A
H
Chimpanzee
Pan troglodytes
XP_514446
364
39904
S265
I
L
D
H
R
E
G
S
G
P
I
A
F
A
H
Rhesus Macaque
Macaca mulatta
XP_001118147
340
37885
S241
I
L
D
H
H
E
G
S
G
P
I
A
F
A
H
Dog
Lupus familis
XP_536142
339
37199
S240
I
L
D
H
N
E
G
S
G
P
I
A
F
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0T2
339
37140
S240
I
L
G
H
S
E
G
S
G
P
I
A
F
A
H
Rat
Rattus norvegicus
Q9JIM4
339
37178
S240
I
L
D
H
S
E
G
S
G
P
V
A
F
A
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423122
309
33303
S210
I
L
S
H
V
E
G
S
G
P
T
A
F
A
H
Frog
Xenopus laevis
Q6GQJ8
209
23467
V118
W
E
D
S
L
S
A
V
R
G
A
R
T
C
A
Zebra Danio
Brachydanio rerio
Q566R7
183
20613
V92
L
V
H
C
L
A
G
V
S
R
S
V
T
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608332
387
43724
D254
V
L
E
H
K
P
R
D
R
P
P
Q
E
V
V
Honey Bee
Apis mellifera
XP_396430
347
39479
E237
I
L
P
H
M
P
K
E
K
Q
I
W
R
H
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203068
264
29514
E173
E
E
I
H
S
R
E
E
I
P
K
D
L
L
A
Poplar Tree
Populus trichocarpa
XP_002308890
352
39035
Q254
C
R
R
V
V
A
L
Q
E
N
V
M
D
H
V
Maize
Zea mays
NP_001130071
354
39026
G258
R
R
V
I
A
V
E
G
N
V
I
S
H
V
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02256
364
41167
S256
D
P
P
S
K
E
S
S
E
G
H
F
I
K
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
96.1
85.2
N.A.
83.5
82.6
N.A.
N.A.
58.5
20.8
21.7
N.A.
31.7
31.9
N.A.
26.4
Protein Similarity:
100
93.4
96.4
89.1
N.A.
89.7
89.1
N.A.
N.A.
70.5
36.1
33.5
N.A.
48.5
49.8
N.A.
43.8
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
80
6.6
6.6
N.A.
20
26.6
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
93.3
N.A.
N.A.
80
6.6
20
N.A.
40
26.6
N.A.
13.3
Percent
Protein Identity:
37.2
34.7
N.A.
N.A.
26.6
N.A.
Protein Similarity:
55.4
51.9
N.A.
N.A.
46.9
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
6.6
13.3
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
14
7
0
0
0
7
47
0
47
14
% A
% Cys:
7
0
0
7
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
0
40
0
0
0
0
7
0
0
0
7
7
0
0
% D
% Glu:
7
14
7
0
0
54
14
14
14
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
47
0
0
% F
% Gly:
0
0
7
0
0
0
54
7
47
14
0
0
0
0
0
% G
% His:
0
0
7
67
7
0
0
0
0
0
7
0
7
14
47
% H
% Ile:
54
0
7
7
0
0
0
0
7
0
47
0
7
0
7
% I
% Lys:
0
0
0
0
14
0
7
0
7
0
7
0
0
7
0
% K
% Leu:
7
60
0
0
14
0
7
0
0
0
0
0
7
14
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
7
0
0
0
0
0
% N
% Pro:
0
7
14
0
0
14
0
0
0
60
7
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
7
0
7
0
7
0
0
0
% Q
% Arg:
7
14
7
0
14
7
7
0
14
7
0
7
7
0
7
% R
% Ser:
0
0
7
14
20
7
7
54
7
0
7
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
7
0
14
0
0
% T
% Val:
7
7
7
7
14
7
0
14
0
7
14
7
0
14
20
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _