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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP12 All Species: 16.36
Human Site: S255 Identified Species: 25.71
UniProt: Q9UNI6 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNI6 NP_009171.1 340 37687 S255 H K R M T P S S M L T T G R Q
Chimpanzee Pan troglodytes XP_514446 364 39904 S279 H K R M T P S S M L T T G R Q
Rhesus Macaque Macaca mulatta XP_001118147 340 37885 F255 H K R M T S S F M L T T G R Q
Dog Lupus familis XP_536142 339 37199 F254 H K R V T P S F T L T T G S Q
Cat Felis silvestris
Mouse Mus musculus Q9D0T2 339 37140 S254 H K R T A P S S V L T T G S Q
Rat Rattus norvegicus Q9JIM4 339 37178 S254 H K R T G L S S V L T T G N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423122 309 33303 T224 H K R I T E S T H L R G S G P
Frog Xenopus laevis Q6GQJ8 209 23467 Q132 A N P N M G F Q K Q L E D F G
Zebra Danio Brachydanio rerio Q566R7 183 20613 V106 V V A Y I M T V T T L G W Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608332 387 43724 V268 V P K E K E E V A A A K L P A
Honey Bee Apis mellifera XP_396430 347 39479 K251 I S S R K T S K Q S K P S H E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203068 264 29514 S187 A S D P A S S S P N P A G D N
Poplar Tree Populus trichocarpa XP_002308890 352 39035 S268 V P G E G E T S F A W S K Q K
Maize Zea mays NP_001130071 354 39026 F272 P G E G E S C F D W N R R K S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02256 364 41167 I270 R A A N S H R I I D I Q E S Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 96.1 85.2 N.A. 83.5 82.6 N.A. N.A. 58.5 20.8 21.7 N.A. 31.7 31.9 N.A. 26.4
Protein Similarity: 100 93.4 96.4 89.1 N.A. 89.7 89.1 N.A. N.A. 70.5 36.1 33.5 N.A. 48.5 49.8 N.A. 43.8
P-Site Identity: 100 100 86.6 73.3 N.A. 73.3 66.6 N.A. N.A. 40 0 0 N.A. 0 6.6 N.A. 20
P-Site Similarity: 100 100 86.6 80 N.A. 80 73.3 N.A. N.A. 53.3 0 20 N.A. 6.6 13.3 N.A. 20
Percent
Protein Identity: 37.2 34.7 N.A. N.A. 26.6 N.A.
Protein Similarity: 55.4 51.9 N.A. N.A. 46.9 N.A.
P-Site Identity: 6.6 0 N.A. N.A. 6.6 N.A.
P-Site Similarity: 33.3 6.6 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 14 0 14 0 0 0 7 14 7 7 0 0 7 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 7 7 0 0 7 7 0 % D
% Glu: 0 0 7 14 7 20 7 0 0 0 0 7 7 0 14 % E
% Phe: 0 0 0 0 0 0 7 20 7 0 0 0 0 7 0 % F
% Gly: 0 7 7 7 14 7 0 0 0 0 0 14 47 7 7 % G
% His: 47 0 0 0 0 7 0 0 7 0 0 0 0 7 0 % H
% Ile: 7 0 0 7 7 0 0 7 7 0 7 0 0 0 0 % I
% Lys: 0 47 7 0 14 0 0 7 7 0 7 7 7 7 7 % K
% Leu: 0 0 0 0 0 7 0 0 0 47 14 0 7 0 0 % L
% Met: 0 0 0 20 7 7 0 0 20 0 0 0 0 0 0 % M
% Asn: 0 7 0 14 0 0 0 0 0 7 7 0 0 7 7 % N
% Pro: 7 14 7 7 0 27 0 0 7 0 7 7 0 7 7 % P
% Gln: 0 0 0 0 0 0 0 7 7 7 0 7 0 14 47 % Q
% Arg: 7 0 47 7 0 0 7 0 0 0 7 7 7 20 0 % R
% Ser: 0 14 7 0 7 20 60 40 0 7 0 7 14 20 7 % S
% Thr: 0 0 0 14 34 7 14 7 14 7 40 40 0 0 0 % T
% Val: 20 7 0 7 0 0 0 14 14 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 7 0 7 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _