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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP12 All Species: 13.03
Human Site: S65 Identified Species: 20.48
UniProt: Q9UNI6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNI6 NP_009171.1 340 37687 S65 T V D S E E P S F K A G P G V
Chimpanzee Pan troglodytes XP_514446 364 39904 S78 T V D S E E P S F K A G P G V
Rhesus Macaque Macaca mulatta XP_001118147 340 37885 S65 T V D S E E P S F K A G P G V
Dog Lupus familis XP_536142 339 37199 D64 A V D S E E P D L T A G A G T
Cat Felis silvestris
Mouse Mus musculus Q9D0T2 339 37140 F65 T V D S E P A F P A G A G F E
Rat Rattus norvegicus Q9JIM4 339 37178 F65 T V D S E P A F P A G A G F E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423122 309 33303 S61 E P G A D L L S R L D E C A A
Frog Xenopus laevis Q6GQJ8 209 23467
Zebra Danio Brachydanio rerio Q566R7 183 20613
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608332 387 43724 P77 T L D S V P L P Q H I L E A S
Honey Bee Apis mellifera XP_396430 347 39479 I62 S C P L P R K I Q E L L P N L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203068 264 29514 L26 A A E S E R F L N D R K I S H
Poplar Tree Populus trichocarpa XP_002308890 352 39035 A82 V L Y S L E Y A G K E L K L V
Maize Zea mays NP_001130071 354 39026 T72 G E E G A A P T A A V P P G T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02256 364 41167 T73 P I D D D D V T D V L Q Y F D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 96.1 85.2 N.A. 83.5 82.6 N.A. N.A. 58.5 20.8 21.7 N.A. 31.7 31.9 N.A. 26.4
Protein Similarity: 100 93.4 96.4 89.1 N.A. 89.7 89.1 N.A. N.A. 70.5 36.1 33.5 N.A. 48.5 49.8 N.A. 43.8
P-Site Identity: 100 100 100 60 N.A. 33.3 33.3 N.A. N.A. 6.6 0 0 N.A. 20 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 60 N.A. 33.3 33.3 N.A. N.A. 20 0 0 N.A. 26.6 26.6 N.A. 20
Percent
Protein Identity: 37.2 34.7 N.A. N.A. 26.6 N.A.
Protein Similarity: 55.4 51.9 N.A. N.A. 46.9 N.A.
P-Site Identity: 26.6 20 N.A. N.A. 6.6 N.A.
P-Site Similarity: 40 33.3 N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 7 7 7 14 7 7 20 27 14 7 14 7 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 54 7 14 7 0 7 7 7 7 0 0 0 7 % D
% Glu: 7 7 14 0 47 34 0 0 0 7 7 7 7 0 14 % E
% Phe: 0 0 0 0 0 0 7 14 20 0 0 0 0 20 0 % F
% Gly: 7 0 7 7 0 0 0 0 7 0 14 27 14 34 0 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % H
% Ile: 0 7 0 0 0 0 0 7 0 0 7 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 7 0 0 27 0 7 7 0 0 % K
% Leu: 0 14 0 7 7 7 14 7 7 7 14 20 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % N
% Pro: 7 7 7 0 7 20 34 7 14 0 0 7 34 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 14 0 0 7 0 0 0 % Q
% Arg: 0 0 0 0 0 14 0 0 7 0 7 0 0 0 0 % R
% Ser: 7 0 0 60 0 0 0 27 0 0 0 0 0 7 7 % S
% Thr: 40 0 0 0 0 0 0 14 0 7 0 0 0 0 14 % T
% Val: 7 40 0 0 7 0 7 0 0 7 7 0 0 0 27 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 7 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _