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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP12
All Species:
18.18
Human Site:
Y170
Identified Species:
28.57
UniProt:
Q9UNI6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNI6
NP_009171.1
340
37687
Y170
K
L
Y
Q
A
M
G
Y
E
V
D
T
S
S
A
Chimpanzee
Pan troglodytes
XP_514446
364
39904
Y194
K
L
Y
Q
A
M
G
Y
E
V
D
T
S
S
A
Rhesus Macaque
Macaca mulatta
XP_001118147
340
37885
Y170
K
L
Y
Q
A
M
G
Y
E
V
D
T
S
S
A
Dog
Lupus familis
XP_536142
339
37199
Y169
K
L
Y
Q
A
M
G
Y
E
V
D
T
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0T2
339
37140
Y169
K
L
Y
E
A
M
G
Y
E
V
D
T
S
S
A
Rat
Rattus norvegicus
Q9JIM4
339
37178
H169
K
L
Y
E
A
M
G
H
E
V
H
T
S
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423122
309
33303
C139
K
L
Y
E
A
M
G
C
A
V
D
S
S
S
A
Frog
Xenopus laevis
Q6GQJ8
209
23467
M48
A
R
P
M
L
E
G
M
K
Y
L
C
I
P
A
Zebra Danio
Brachydanio rerio
Q566R7
183
20613
D22
G
N
F
K
D
A
R
D
R
E
Q
L
A
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608332
387
43724
C181
K
L
F
R
R
M
G
C
K
I
D
P
N
C
Q
Honey Bee
Apis mellifera
XP_396430
347
39479
F164
K
L
Y
E
E
M
C
F
G
I
D
N
T
N
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203068
264
29514
A102
G
V
S
R
S
S
S
A
V
I
A
Y
I
M
Y
Poplar Tree
Populus trichocarpa
XP_002308890
352
39035
F182
K
M
F
E
E
M
G
F
K
V
D
H
A
S
P
Maize
Zea mays
NP_001130071
354
39026
F187
K
L
F
E
E
M
G
F
K
V
D
T
S
S
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02256
364
41167
D173
L
F
E
K
M
G
G
D
F
V
D
F
D
N
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
96.1
85.2
N.A.
83.5
82.6
N.A.
N.A.
58.5
20.8
21.7
N.A.
31.7
31.9
N.A.
26.4
Protein Similarity:
100
93.4
96.4
89.1
N.A.
89.7
89.1
N.A.
N.A.
70.5
36.1
33.5
N.A.
48.5
49.8
N.A.
43.8
P-Site Identity:
100
100
100
100
N.A.
93.3
80
N.A.
N.A.
73.3
13.3
0
N.A.
33.3
33.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
86.6
20
20
N.A.
66.6
66.6
N.A.
26.6
Percent
Protein Identity:
37.2
34.7
N.A.
N.A.
26.6
N.A.
Protein Similarity:
55.4
51.9
N.A.
N.A.
46.9
N.A.
P-Site Identity:
40
60
N.A.
N.A.
20
N.A.
P-Site Similarity:
80
86.6
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
47
7
0
7
7
0
7
0
14
0
54
% A
% Cys:
0
0
0
0
0
0
7
14
0
0
0
7
0
7
0
% C
% Asp:
0
0
0
0
7
0
0
14
0
0
74
0
7
0
0
% D
% Glu:
0
0
7
40
20
7
0
0
40
7
0
0
0
0
0
% E
% Phe:
0
7
27
0
0
0
0
20
7
0
0
7
0
0
0
% F
% Gly:
14
0
0
0
0
7
80
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
7
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
20
0
0
14
0
0
% I
% Lys:
74
0
0
14
0
0
0
0
27
0
0
0
0
0
0
% K
% Leu:
7
67
0
0
7
0
0
0
0
0
7
7
0
0
0
% L
% Met:
0
7
0
7
7
74
0
7
0
0
0
0
0
7
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
7
7
14
7
% N
% Pro:
0
0
7
0
0
0
0
0
0
0
0
7
0
7
20
% P
% Gln:
0
0
0
27
0
0
0
0
0
0
7
0
0
0
7
% Q
% Arg:
0
7
0
14
7
0
7
0
7
0
0
0
0
7
0
% R
% Ser:
0
0
7
0
7
7
7
0
0
0
0
7
54
60
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
47
7
0
0
% T
% Val:
0
7
0
0
0
0
0
0
7
67
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
54
0
0
0
0
34
0
7
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _