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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP12
All Species:
40
Human Site:
Y179
Identified Species:
62.86
UniProt:
Q9UNI6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNI6
NP_009171.1
340
37687
Y179
V
D
T
S
S
A
I
Y
K
Q
Y
R
L
Q
K
Chimpanzee
Pan troglodytes
XP_514446
364
39904
Y203
V
D
T
S
S
A
I
Y
K
Q
Y
R
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001118147
340
37885
Y179
V
D
T
S
S
A
I
Y
K
Q
Y
R
L
Q
K
Dog
Lupus familis
XP_536142
339
37199
Y178
V
D
T
S
S
A
I
Y
K
Q
Y
R
L
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0T2
339
37140
Y178
V
D
T
S
S
A
F
Y
K
Q
Y
R
L
Q
K
Rat
Rattus norvegicus
Q9JIM4
339
37178
Y178
V
H
T
S
S
A
V
Y
K
Q
Y
R
L
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423122
309
33303
Y148
V
D
S
S
S
A
L
Y
K
Q
H
R
L
Q
V
Frog
Xenopus laevis
Q6GQJ8
209
23467
D57
Y
L
C
I
P
A
S
D
S
P
S
Q
N
L
I
Zebra Danio
Brachydanio rerio
Q566R7
183
20613
I31
E
Q
L
A
R
N
N
I
T
H
I
L
S
I
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608332
387
43724
Y190
I
D
P
N
C
Q
R
Y
K
I
H
R
L
R
L
Honey Bee
Apis mellifera
XP_396430
347
39479
F173
I
D
N
T
N
V
Q
F
K
M
Y
K
L
Q
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203068
264
29514
E111
I
A
Y
I
M
Y
K
E
K
C
P
L
V
T
A
Poplar Tree
Populus trichocarpa
XP_002308890
352
39035
Y191
V
D
H
A
S
P
I
Y
K
R
F
R
L
K
A
Maize
Zea mays
NP_001130071
354
39026
Y196
V
D
T
S
S
P
L
Y
K
R
F
R
L
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02256
364
41167
Y182
V
D
F
D
N
P
A
Y
K
Q
W
K
L
K
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
96.1
85.2
N.A.
83.5
82.6
N.A.
N.A.
58.5
20.8
21.7
N.A.
31.7
31.9
N.A.
26.4
Protein Similarity:
100
93.4
96.4
89.1
N.A.
89.7
89.1
N.A.
N.A.
70.5
36.1
33.5
N.A.
48.5
49.8
N.A.
43.8
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
N.A.
73.3
6.6
0
N.A.
33.3
33.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
13.3
6.6
N.A.
60
66.6
N.A.
20
Percent
Protein Identity:
37.2
34.7
N.A.
N.A.
26.6
N.A.
Protein Similarity:
55.4
51.9
N.A.
N.A.
46.9
N.A.
P-Site Identity:
53.3
60
N.A.
N.A.
40
N.A.
P-Site Similarity:
80
86.6
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
14
0
54
7
0
0
0
0
0
0
0
14
% A
% Cys:
0
0
7
0
7
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
74
0
7
0
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
0
0
7
7
0
0
14
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
7
0
0
0
0
0
0
7
14
0
0
0
7
% H
% Ile:
20
0
0
14
0
0
34
7
0
7
7
0
0
7
14
% I
% Lys:
0
0
0
0
0
0
7
0
87
0
0
14
0
20
40
% K
% Leu:
0
7
7
0
0
0
14
0
0
0
0
14
80
7
14
% L
% Met:
0
0
0
0
7
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
7
14
7
7
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
7
0
7
20
0
0
0
7
7
0
0
0
0
% P
% Gln:
0
7
0
0
0
7
7
0
0
54
0
7
0
54
7
% Q
% Arg:
0
0
0
0
7
0
7
0
0
14
0
67
0
7
0
% R
% Ser:
0
0
7
54
60
0
7
0
7
0
7
0
7
0
0
% S
% Thr:
0
0
47
7
0
0
0
0
7
0
0
0
0
7
0
% T
% Val:
67
0
0
0
0
7
7
0
0
0
0
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
7
0
7
0
0
7
0
74
0
0
47
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _