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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUSP12 All Species: 22.42
Human Site: Y191 Identified Species: 35.24
UniProt: Q9UNI6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNI6 NP_009171.1 340 37687 Y191 L Q K V T E K Y P E L Q N L P
Chimpanzee Pan troglodytes XP_514446 364 39904 Y215 L Q K V T E K Y P E L Q N L P
Rhesus Macaque Macaca mulatta XP_001118147 340 37885 Y191 L Q K V T E K Y P E L Q N L P
Dog Lupus familis XP_536142 339 37199 Y190 L Q K V T E K Y P E L Q N L P
Cat Felis silvestris
Mouse Mus musculus Q9D0T2 339 37140 C190 L Q K V T E K C P K L W N L P
Rat Rattus norvegicus Q9JIM4 339 37178 Y190 L Q K V T E K Y P E L R N L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423122 309 33303 F160 L Q V L T E R F S E L Q D L P
Frog Xenopus laevis Q6GQJ8 209 23467 D69 N L I Q H F K D S I A F I H E
Zebra Danio Brachydanio rerio Q566R7 183 20613 P43 S I H D T A A P I L Q E M T Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608332 387 43724 M202 L R L A G E Q M R K A K I L P
Honey Bee Apis mellifera XP_396430 347 39479 V185 L Q I A A D K V R K A K I L P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203068 264 29514 V123 V T A L K K V V D K H S Q T C
Poplar Tree Populus trichocarpa XP_002308890 352 39035 Y203 L K A L G E F Y N R G E K I D
Maize Zea mays NP_001130071 354 39026 Y208 L K L L G Q S Y I S G E K I S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q02256 364 41167 D194 L K Q S I K L D P S G S E L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 96.1 85.2 N.A. 83.5 82.6 N.A. N.A. 58.5 20.8 21.7 N.A. 31.7 31.9 N.A. 26.4
Protein Similarity: 100 93.4 96.4 89.1 N.A. 89.7 89.1 N.A. N.A. 70.5 36.1 33.5 N.A. 48.5 49.8 N.A. 43.8
P-Site Identity: 100 100 100 100 N.A. 80 93.3 N.A. N.A. 60 6.6 6.6 N.A. 26.6 33.3 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 86.6 100 N.A. N.A. 86.6 6.6 13.3 N.A. 53.3 53.3 N.A. 26.6
Percent
Protein Identity: 37.2 34.7 N.A. N.A. 26.6 N.A.
Protein Similarity: 55.4 51.9 N.A. N.A. 46.9 N.A.
P-Site Identity: 20 13.3 N.A. N.A. 20 N.A.
P-Site Similarity: 46.6 46.6 N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 14 7 7 7 0 0 0 20 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % C
% Asp: 0 0 0 7 0 7 0 14 7 0 0 0 7 0 7 % D
% Glu: 0 0 0 0 0 60 0 0 0 40 0 20 7 0 7 % E
% Phe: 0 0 0 0 0 7 7 7 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 20 0 0 0 0 0 20 0 0 0 0 % G
% His: 0 0 7 0 7 0 0 0 0 0 7 0 0 7 0 % H
% Ile: 0 7 14 0 7 0 0 0 14 7 0 0 20 14 0 % I
% Lys: 0 20 40 0 7 14 54 0 0 27 0 14 14 0 0 % K
% Leu: 80 7 14 27 0 0 7 0 0 7 47 0 0 67 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 7 0 0 0 40 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 47 0 0 0 0 0 60 % P
% Gln: 0 54 7 7 0 7 7 0 0 0 7 34 7 0 0 % Q
% Arg: 0 7 0 0 0 0 7 0 14 7 0 7 0 0 0 % R
% Ser: 7 0 0 7 0 0 7 0 14 14 0 14 0 0 7 % S
% Thr: 0 7 0 0 54 0 0 0 0 0 0 0 0 14 0 % T
% Val: 7 0 7 40 0 0 7 14 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 47 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _