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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP12
All Species:
22.42
Human Site:
Y191
Identified Species:
35.24
UniProt:
Q9UNI6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNI6
NP_009171.1
340
37687
Y191
L
Q
K
V
T
E
K
Y
P
E
L
Q
N
L
P
Chimpanzee
Pan troglodytes
XP_514446
364
39904
Y215
L
Q
K
V
T
E
K
Y
P
E
L
Q
N
L
P
Rhesus Macaque
Macaca mulatta
XP_001118147
340
37885
Y191
L
Q
K
V
T
E
K
Y
P
E
L
Q
N
L
P
Dog
Lupus familis
XP_536142
339
37199
Y190
L
Q
K
V
T
E
K
Y
P
E
L
Q
N
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0T2
339
37140
C190
L
Q
K
V
T
E
K
C
P
K
L
W
N
L
P
Rat
Rattus norvegicus
Q9JIM4
339
37178
Y190
L
Q
K
V
T
E
K
Y
P
E
L
R
N
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423122
309
33303
F160
L
Q
V
L
T
E
R
F
S
E
L
Q
D
L
P
Frog
Xenopus laevis
Q6GQJ8
209
23467
D69
N
L
I
Q
H
F
K
D
S
I
A
F
I
H
E
Zebra Danio
Brachydanio rerio
Q566R7
183
20613
P43
S
I
H
D
T
A
A
P
I
L
Q
E
M
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608332
387
43724
M202
L
R
L
A
G
E
Q
M
R
K
A
K
I
L
P
Honey Bee
Apis mellifera
XP_396430
347
39479
V185
L
Q
I
A
A
D
K
V
R
K
A
K
I
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203068
264
29514
V123
V
T
A
L
K
K
V
V
D
K
H
S
Q
T
C
Poplar Tree
Populus trichocarpa
XP_002308890
352
39035
Y203
L
K
A
L
G
E
F
Y
N
R
G
E
K
I
D
Maize
Zea mays
NP_001130071
354
39026
Y208
L
K
L
L
G
Q
S
Y
I
S
G
E
K
I
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q02256
364
41167
D194
L
K
Q
S
I
K
L
D
P
S
G
S
E
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
96.1
85.2
N.A.
83.5
82.6
N.A.
N.A.
58.5
20.8
21.7
N.A.
31.7
31.9
N.A.
26.4
Protein Similarity:
100
93.4
96.4
89.1
N.A.
89.7
89.1
N.A.
N.A.
70.5
36.1
33.5
N.A.
48.5
49.8
N.A.
43.8
P-Site Identity:
100
100
100
100
N.A.
80
93.3
N.A.
N.A.
60
6.6
6.6
N.A.
26.6
33.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
100
N.A.
N.A.
86.6
6.6
13.3
N.A.
53.3
53.3
N.A.
26.6
Percent
Protein Identity:
37.2
34.7
N.A.
N.A.
26.6
N.A.
Protein Similarity:
55.4
51.9
N.A.
N.A.
46.9
N.A.
P-Site Identity:
20
13.3
N.A.
N.A.
20
N.A.
P-Site Similarity:
46.6
46.6
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
14
7
7
7
0
0
0
20
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
7
0
7
0
14
7
0
0
0
7
0
7
% D
% Glu:
0
0
0
0
0
60
0
0
0
40
0
20
7
0
7
% E
% Phe:
0
0
0
0
0
7
7
7
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
20
0
0
0
0
0
20
0
0
0
0
% G
% His:
0
0
7
0
7
0
0
0
0
0
7
0
0
7
0
% H
% Ile:
0
7
14
0
7
0
0
0
14
7
0
0
20
14
0
% I
% Lys:
0
20
40
0
7
14
54
0
0
27
0
14
14
0
0
% K
% Leu:
80
7
14
27
0
0
7
0
0
7
47
0
0
67
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
7
0
0
0
40
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
47
0
0
0
0
0
60
% P
% Gln:
0
54
7
7
0
7
7
0
0
0
7
34
7
0
0
% Q
% Arg:
0
7
0
0
0
0
7
0
14
7
0
7
0
0
0
% R
% Ser:
7
0
0
7
0
0
7
0
14
14
0
14
0
0
7
% S
% Thr:
0
7
0
0
54
0
0
0
0
0
0
0
0
14
0
% T
% Val:
7
0
7
40
0
0
7
14
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _