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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANGEL1
All Species:
18.79
Human Site:
S421
Identified Species:
37.58
UniProt:
Q9UNK9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNK9
NP_056120.2
670
75276
S421
V
D
K
V
A
R
L
S
D
G
S
H
C
P
I
Chimpanzee
Pan troglodytes
XP_001163194
670
75287
S421
V
D
K
V
A
R
L
S
D
G
S
H
C
P
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547922
652
73254
S403
V
D
K
V
A
R
L
S
D
G
S
H
C
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCU0
667
75235
S418
V
D
K
V
A
R
L
S
D
G
S
H
C
P
I
Rat
Rattus norvegicus
B2RYM0
667
75323
S418
V
D
K
V
A
R
L
S
D
G
S
H
C
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508122
689
76877
E440
V
D
K
M
A
R
L
E
D
D
S
Y
C
P
I
Chicken
Gallus gallus
NP_001026376
662
73558
F400
V
A
N
T
H
V
L
F
N
P
R
R
G
D
I
Frog
Xenopus laevis
Q5XH73
550
62606
N304
F
N
Q
I
A
M
A
N
S
E
G
S
E
A
M
Zebra Danio
Brachydanio rerio
Q5RGT6
569
65312
L323
D
N
V
G
L
I
V
L
L
R
P
I
D
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24239
354
40288
E108
R
Q
Q
N
L
L
R
E
L
L
K
L
D
P
D
Honey Bee
Apis mellifera
XP_395873
481
55813
A235
P
Q
I
Q
L
V
I
A
T
T
H
L
L
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797626
569
64453
T323
H
Q
L
C
V
A
N
T
H
L
L
W
N
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
90.1
N.A.
90.5
90.4
N.A.
66.1
60.2
20.8
35.6
N.A.
22
26.1
N.A.
28
Protein Similarity:
100
99.8
N.A.
93.2
N.A.
94.9
94.9
N.A.
77.2
72.8
35.8
51
N.A.
33.5
40.1
N.A.
46.1
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
73.3
20
6.6
6.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
26.6
40
20
N.A.
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
59
9
9
9
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
50
0
0
% C
% Asp:
9
50
0
0
0
0
0
0
50
9
0
0
17
9
9
% D
% Glu:
0
0
0
0
0
0
0
17
0
9
0
0
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
42
9
0
9
0
0
% G
% His:
9
0
0
0
9
0
0
0
9
0
9
42
0
0
9
% H
% Ile:
0
0
9
9
0
9
9
0
0
0
0
9
0
0
59
% I
% Lys:
0
0
50
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
9
0
25
9
59
9
17
17
9
17
9
0
0
% L
% Met:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
17
9
9
0
0
9
9
9
0
0
0
9
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
9
9
0
0
75
0
% P
% Gln:
0
25
17
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
50
9
0
0
9
9
9
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
42
9
0
50
9
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
9
9
9
0
0
0
0
0
% T
% Val:
59
0
9
42
9
17
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _