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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ING4 All Species: 24.55
Human Site: S124 Identified Species: 54
UniProt: Q9UNL4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNL4 NP_001121054.1 249 28530 S124 E S S D Y D S S S S K G K K K
Chimpanzee Pan troglodytes XP_001169091 249 28482 S124 E S S D Y D S S S S K G K K K
Rhesus Macaque Macaca mulatta XP_001118270 236 27029 S112 S S D Y D S S S S K G K K K G
Dog Lupus familis XP_853656 249 28512 S124 E S S D Y D S S S S K G K K K
Cat Felis silvestris
Mouse Mus musculus Q8C0D7 249 28510 S124 E S S D Y D S S S S K G K K K
Rat Rattus norvegicus Q498T3 421 46906 S291 T L T Q N A S S S A A D S R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516059 236 27318 D112 A D L K D K M D G S D F E S P
Chicken Gallus gallus Q5ZKY4 249 28538 S124 E S S D Y D S S S S K G K K K
Frog Xenopus laevis Q7ZX31 416 46165 T286 S T L T Q T L T S S A T T D S
Zebra Danio Brachydanio rerio NP_001018304 250 28690 S125 S T D Y D S T S S K G N K S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38806 282 32068 A150 S V K K R R A A S S S G S V P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 94.7 99.1 N.A. 99.1 28.2 N.A. 68.2 96.7 26.9 82 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.5 94.7 99.1 N.A. 99.5 42.2 N.A. 81.1 98.8 40.8 91.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 40 100 N.A. 100 20 N.A. 6.6 100 13.3 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 40 100 N.A. 100 40 N.A. 13.3 100 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 10 10 0 10 19 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 19 46 28 46 0 10 0 0 10 10 0 10 10 % D
% Glu: 46 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 19 55 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 19 0 10 0 0 0 19 46 10 64 55 46 % K
% Leu: 0 10 19 0 0 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % P
% Gln: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 10 10 0 0 0 0 0 0 0 10 0 % R
% Ser: 37 55 46 0 0 19 64 73 91 73 10 0 19 19 19 % S
% Thr: 10 19 10 10 0 10 10 10 0 0 0 10 10 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 19 46 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _