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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAF1 All Species: 41.21
Human Site: S574 Identified Species: 82.42
UniProt: Q9UNN5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNN5 NP_008982.1 650 73954 S574 E E N A E P V S K L R I R T P
Chimpanzee Pan troglodytes XP_513397 650 73922 S574 E E N A E P V S K L R I R T P
Rhesus Macaque Macaca mulatta XP_001104146 802 90758 S703 E E N A E P V S K L R I R T P
Dog Lupus familis XP_849822 649 73803 S573 E E N A E P V S K L R I R T P
Cat Felis silvestris
Mouse Mus musculus P54731 649 73816 S573 E E N A E P V S K L R I R T P
Rat Rattus norvegicus Q924K2 649 73727 S573 E E N A E P V S K L R I R T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509181 657 73828 S581 E E S T E P V S K L R I R T P
Chicken Gallus gallus XP_422464 646 73386 S570 E E S T E S V S K L R I R T P
Frog Xenopus laevis NP_001085205 655 74349 S579 L E E S E P L S K L R I R T P
Zebra Danio Brachydanio rerio NP_998138 673 75349 S597 E E G G E P I S K L R I R T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611080 695 78422 S620 S E Q E T G T S K I R V R K P
Honey Bee Apis mellifera XP_392750 647 74035 L572 Q G T G D G V L K V R V R L P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 78.4 98.1 N.A. 95.6 95.5 N.A. 90.1 91.5 83.3 77.8 N.A. 36.1 38 N.A. N.A.
Protein Similarity: 100 100 79.4 99.2 N.A. 97.8 97.8 N.A. 94.6 95.6 92.2 86 N.A. 56.1 61 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 86.6 80 73.3 80 N.A. 40 33.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 86.6 86.6 86.6 N.A. 53.3 60 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 75 92 9 9 84 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 9 17 0 17 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 9 0 84 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 100 0 0 0 0 9 0 % K
% Leu: 9 0 0 0 0 0 9 9 0 84 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 100 % P
% Gln: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 100 0 100 0 0 % R
% Ser: 9 0 17 9 0 9 0 92 0 0 0 0 0 0 0 % S
% Thr: 0 0 9 17 9 0 9 0 0 0 0 0 0 84 0 % T
% Val: 0 0 0 0 0 0 75 0 0 9 0 17 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _