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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMELESS
All Species:
27.88
Human Site:
S497
Identified Species:
61.33
UniProt:
Q9UNS1
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNS1
NP_003911.2
1208
138630
S497
D
E
R
C
Q
P
R
S
F
L
R
D
L
V
E
Chimpanzee
Pan troglodytes
XP_509535
1209
138911
S497
D
E
R
C
Q
P
R
S
F
L
R
D
L
V
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538233
1446
163698
S726
D
E
R
C
Q
P
R
S
F
L
R
D
L
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1X4
1197
137484
S497
D
E
R
Y
H
P
R
S
F
L
R
D
L
V
E
Rat
Rattus norvegicus
Q9Z2Y1
1205
138547
S497
D
E
R
Y
H
P
R
S
F
L
C
D
L
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512607
1213
138721
S492
D
E
T
R
Q
P
R
S
F
L
C
D
L
V
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922924
1278
147885
S497
D
E
R
L
Q
P
R
S
F
L
R
D
L
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524341
1384
159345
V495
N
E
A
H
S
T
K
V
F
L
R
D
V
V
E
Honey Bee
Apis mellifera
XP_623203
520
60789
Nematode Worm
Caenorhab. elegans
NP_499594
1353
156992
N495
S
S
S
V
L
S
N
N
F
L
R
E
L
V
L
Sea Urchin
Strong. purpuratus
XP_784350
1529
176104
T503
N
E
V
K
C
T
R
T
Y
L
K
D
L
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.6
N.A.
83.8
81.4
N.A.
70.2
N.A.
N.A.
59.5
N.A.
33.1
20.3
23.2
38
Protein Similarity:
100
99.7
N.A.
77.9
N.A.
90.5
89.6
N.A.
80.4
N.A.
N.A.
73.6
N.A.
53
30.7
43
55.7
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
80
N.A.
N.A.
93.3
N.A.
46.6
0
33.3
40
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
80
N.A.
80
N.A.
N.A.
93.3
N.A.
66.6
0
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
28
10
0
0
0
0
0
19
0
0
0
0
% C
% Asp:
64
0
0
0
0
0
0
0
0
0
0
82
0
0
0
% D
% Glu:
0
82
0
0
0
0
0
0
0
0
0
10
0
0
82
% E
% Phe:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
19
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% I
% Lys:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
10
10
0
0
0
0
91
0
0
82
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
64
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
55
10
0
0
73
0
0
0
64
0
0
0
0
% R
% Ser:
10
10
10
0
10
10
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
0
0
19
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
10
10
0
0
0
10
0
0
0
0
10
73
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
19
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _