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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS3
All Species:
46.67
Human Site:
S410
Identified Species:
68.44
UniProt:
Q9UNS2
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNS2
NP_003644.2
423
47873
S410
F
V
Q
K
S
M
G
S
Q
E
D
D
S
G
N
Chimpanzee
Pan troglodytes
XP_001160462
403
45708
S390
F
V
Q
K
S
M
G
S
Q
E
D
D
S
G
N
Rhesus Macaque
Macaca mulatta
XP_001089619
403
45805
S390
F
V
Q
K
S
M
G
S
Q
E
D
D
S
G
N
Dog
Lupus familis
XP_536667
423
47885
S410
F
V
Q
K
S
M
G
S
Q
E
D
D
S
G
N
Cat
Felis silvestris
Mouse
Mus musculus
O88543
423
47814
S410
F
V
Q
K
S
M
G
S
Q
E
D
D
S
G
N
Rat
Rattus norvegicus
Q68FW9
423
47841
S410
F
V
Q
K
S
M
G
S
Q
E
D
D
S
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510734
403
45736
S390
F
V
Q
K
S
M
G
S
Q
E
D
D
S
G
S
Chicken
Gallus gallus
Q5ZJF1
423
47944
S410
F
V
Q
K
S
M
G
S
Q
E
D
D
S
G
T
Frog
Xenopus laevis
Q7ZTN8
423
47776
S410
F
V
Q
K
S
M
G
S
Q
E
D
D
S
G
S
Zebra Danio
Brachydanio rerio
Q6P2U9
423
47889
T410
F
V
Q
K
S
M
G
T
Q
E
D
D
V
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8SYG2
445
50685
S426
Y
V
K
K
A
L
G
S
Q
D
D
D
L
T
S
Honey Bee
Apis mellifera
XP_624761
445
50628
Q416
Y
V
R
K
A
C
G
Q
N
D
Q
D
D
Q
T
Nematode Worm
Caenorhab. elegans
Q9N425
501
55865
Y484
R
M
R
P
S
V
M
Y
N
E
D
E
G
L
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001149499
424
47039
R408
Y
L
M
T
G
R
D
R
G
R
F
D
Y
D
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W575
429
47723
E410
Y
L
G
K
V
G
R
E
R
Q
R
Y
D
F
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S7G7
497
55199
R458
Y
I
S
H
T
V
K
R
Q
F
D
A
A
R
E
Conservation
Percent
Protein Identity:
100
95.2
93.6
99.7
N.A.
99.5
99.7
N.A.
94.5
98.5
93.8
93.6
N.A.
51
60.9
20.9
N.A.
Protein Similarity:
100
95.2
94.3
99.7
N.A.
100
100
N.A.
95.2
99
97.8
98.1
N.A.
68.7
77
39.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
93.3
80
N.A.
46.6
26.6
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
100
93.3
N.A.
86.6
53.3
53.3
N.A.
Percent
Protein Identity:
N.A.
41.2
N.A.
38.9
N.A.
22.1
Protein Similarity:
N.A.
61
N.A.
57.5
N.A.
39.4
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
13.3
P-Site Similarity:
N.A.
26.6
N.A.
33.3
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
13
82
82
13
7
7
% D
% Glu:
0
0
0
0
0
0
0
7
0
69
0
7
0
0
7
% E
% Phe:
63
0
0
0
0
0
0
0
0
7
7
0
0
7
0
% F
% Gly:
0
0
7
0
7
7
75
0
7
0
0
0
7
63
7
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
82
0
0
7
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
0
0
0
7
0
0
0
0
0
0
7
7
0
% L
% Met:
0
7
7
0
0
63
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
38
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
63
0
0
0
0
7
75
7
7
0
0
7
0
% Q
% Arg:
7
0
13
0
0
7
7
13
7
7
7
0
0
7
0
% R
% Ser:
0
0
7
0
69
0
0
63
0
0
0
0
57
0
32
% S
% Thr:
0
0
0
7
7
0
0
7
0
0
0
0
0
7
13
% T
% Val:
0
75
0
0
7
13
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
32
0
0
0
0
0
0
7
0
0
0
7
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _