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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS3
All Species:
41.17
Human Site:
S421
Identified Species:
60.38
UniProt:
Q9UNS2
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNS2
NP_003644.2
423
47873
S421
D
S
G
N
K
P
S
S
Y
S
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001160462
403
45708
S401
D
S
G
N
K
P
S
S
Y
S
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001089619
403
45805
S401
D
S
G
N
K
P
S
S
Y
S
_
_
_
_
_
Dog
Lupus familis
XP_536667
423
47885
S421
D
S
G
N
K
P
S
S
Y
S
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
O88543
423
47814
S421
D
S
G
N
K
P
S
S
Y
S
_
_
_
_
_
Rat
Rattus norvegicus
Q68FW9
423
47841
S421
D
S
G
N
K
P
S
S
Y
S
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510734
403
45736
S401
D
S
G
S
K
P
S
S
Y
S
_
_
_
_
_
Chicken
Gallus gallus
Q5ZJF1
423
47944
S421
D
S
G
T
K
P
S
S
Y
S
_
_
_
_
_
Frog
Xenopus laevis
Q7ZTN8
423
47776
S421
D
S
G
S
K
P
S
S
Y
S
_
_
_
_
_
Zebra Danio
Brachydanio rerio
Q6P2U9
423
47889
S421
D
V
G
S
K
T
S
S
Y
S
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8SYG2
445
50685
K437
D
L
T
S
Q
H
P
K
T
F
S
G
D
P
T
Honey Bee
Apis mellifera
XP_624761
445
50628
A427
D
D
Q
T
A
G
P
A
P
T
N
V
T
N
V
Nematode Worm
Caenorhab. elegans
Q9N425
501
55865
T495
E
G
L
S
M
P
P
T
E
S
K
F
F
S
_
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001149499
424
47039
V419
D
Y
D
D
F
D
S
V
P
H
K
Y
F
_
_
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W575
429
47723
D421
Y
D
F
G
D
D
F
D
T
V
P
Q
K
F
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S7G7
497
55199
G469
A
A
R
E
H
K
L
G
L
Q
S
A
G
G
G
Conservation
Percent
Protein Identity:
100
95.2
93.6
99.7
N.A.
99.5
99.7
N.A.
94.5
98.5
93.8
93.6
N.A.
51
60.9
20.9
N.A.
Protein Similarity:
100
95.2
94.3
99.7
N.A.
100
100
N.A.
95.2
99
97.8
98.1
N.A.
68.7
77
39.3
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
90
90
90
70
N.A.
6.6
6.6
14.2
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
90
100
80
N.A.
26.6
20
35.7
N.A.
Percent
Protein Identity:
N.A.
41.2
N.A.
38.9
N.A.
22.1
Protein Similarity:
N.A.
61
N.A.
57.5
N.A.
39.4
P-Site Identity:
N.A.
15.3
N.A.
0
N.A.
0
P-Site Similarity:
N.A.
30.7
N.A.
0
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
0
7
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
82
13
7
7
7
13
0
7
0
0
0
0
7
0
0
% D
% Glu:
7
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
7
0
7
0
7
0
0
7
0
7
13
7
0
% F
% Gly:
0
7
63
7
0
7
0
7
0
0
0
7
7
7
7
% G
% His:
0
0
0
0
7
7
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
63
7
0
7
0
0
13
0
7
0
0
% K
% Leu:
0
7
7
0
0
0
7
0
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
38
0
0
0
0
0
0
7
0
0
7
0
% N
% Pro:
0
0
0
0
0
63
19
0
13
0
7
0
0
7
0
% P
% Gln:
0
0
7
0
7
0
0
0
0
7
0
7
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
57
0
32
0
0
69
63
0
69
13
0
0
7
7
% S
% Thr:
0
0
7
13
0
7
0
7
13
7
0
0
7
0
7
% T
% Val:
0
7
0
0
0
0
0
7
0
7
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
0
0
0
0
63
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
63
63
63
69
75
% _