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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS3
All Species:
27.27
Human Site:
Y95
Identified Species:
40
UniProt:
Q9UNS2
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNS2
NP_003644.2
423
47873
Y95
C
N
G
E
H
I
R
Y
A
T
D
T
F
A
G
Chimpanzee
Pan troglodytes
XP_001160462
403
45708
P97
A
L
V
E
R
K
Q
P
L
R
G
I
G
I
L
Rhesus Macaque
Macaca mulatta
XP_001089619
403
45805
P97
A
L
V
E
R
K
Q
P
L
R
G
I
G
I
L
Dog
Lupus familis
XP_536667
423
47885
Y95
C
N
G
E
H
I
R
Y
A
T
D
T
F
A
G
Cat
Felis silvestris
Mouse
Mus musculus
O88543
423
47814
Y95
C
N
G
E
H
I
R
Y
A
T
D
T
F
A
G
Rat
Rattus norvegicus
Q68FW9
423
47841
Y95
C
N
G
E
H
I
R
Y
A
T
D
T
F
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510734
403
45736
P97
A
L
V
E
R
K
Q
P
L
R
G
I
G
I
L
Chicken
Gallus gallus
Q5ZJF1
423
47944
Y95
C
N
G
E
H
I
R
Y
A
T
D
T
F
A
G
Frog
Xenopus laevis
Q7ZTN8
423
47776
Y95
C
N
G
E
H
I
R
Y
A
T
D
T
F
A
G
Zebra Danio
Brachydanio rerio
Q6P2U9
423
47889
Y95
C
N
G
E
H
I
R
Y
A
T
D
T
F
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8SYG2
445
50685
L95
Q
R
N
N
N
E
Q
L
R
Y
A
V
C
A
F
Honey Bee
Apis mellifera
XP_624761
445
50628
N95
Q
E
F
I
I
G
C
N
G
E
Q
V
R
F
A
Nematode Worm
Caenorhab. elegans
Q9N425
501
55865
E112
T
G
T
D
R
A
V
E
L
L
N
H
Y
V
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001149499
424
47039
L99
C
S
A
D
Q
I
R
L
A
P
D
K
F
L
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W575
429
47723
L100
C
D
A
G
Q
I
R
L
A
S
Y
K
F
V
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S7G7
497
55199
C104
F
D
A
R
Q
I
R
C
K
G
S
T
W
S
D
Conservation
Percent
Protein Identity:
100
95.2
93.6
99.7
N.A.
99.5
99.7
N.A.
94.5
98.5
93.8
93.6
N.A.
51
60.9
20.9
N.A.
Protein Similarity:
100
95.2
94.3
99.7
N.A.
100
100
N.A.
95.2
99
97.8
98.1
N.A.
68.7
77
39.3
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
20
0
20
N.A.
Percent
Protein Identity:
N.A.
41.2
N.A.
38.9
N.A.
22.1
Protein Similarity:
N.A.
61
N.A.
57.5
N.A.
39.4
P-Site Identity:
N.A.
40
N.A.
33.3
N.A.
20
P-Site Similarity:
N.A.
53.3
N.A.
46.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
19
0
0
7
0
0
57
0
7
0
0
50
7
% A
% Cys:
57
0
0
0
0
0
7
7
0
0
0
0
7
0
0
% C
% Asp:
0
13
0
13
0
0
0
0
0
0
50
0
0
0
13
% D
% Glu:
0
7
0
63
0
7
0
7
0
7
0
0
0
0
0
% E
% Phe:
7
0
7
0
0
0
0
0
0
0
0
0
57
7
7
% F
% Gly:
0
7
44
7
0
7
0
0
7
7
19
0
19
0
44
% G
% His:
0
0
0
0
44
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
7
7
63
0
0
0
0
0
19
0
19
0
% I
% Lys:
0
0
0
0
0
19
0
0
7
0
0
13
0
0
0
% K
% Leu:
0
19
0
0
0
0
0
19
25
7
0
0
0
7
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
44
7
7
7
0
0
7
0
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
19
0
7
0
0
0
0
0
% P
% Gln:
13
0
0
0
19
0
25
0
0
0
7
0
0
0
0
% Q
% Arg:
0
7
0
7
25
0
63
0
7
19
0
0
7
0
0
% R
% Ser:
0
7
0
0
0
0
0
0
0
7
7
0
0
7
7
% S
% Thr:
7
0
7
0
0
0
0
0
0
44
0
50
0
0
0
% T
% Val:
0
0
19
0
0
0
7
0
0
0
0
13
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
44
0
7
7
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _