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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOVA2 All Species: 15.45
Human Site: S8 Identified Species: 34
UniProt: Q9UNW9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNW9 NP_002507.1 492 49009 S8 M E P E A P D S R K R P L E T
Chimpanzee Pan troglodytes XP_524310 526 52655 L42 T P K I K A T L E G E L F D T
Rhesus Macaque Macaca mulatta XP_001114554 466 47476 Q8 M L S E E D G Q Y F L K V L I
Dog Lupus familis XP_855043 549 55157 Q65 D N V N I T P Q L P H T S V E
Cat Felis silvestris
Mouse Mus musculus Q9JKN6 507 51737 S25 I D L D P P D S R K R P L E A
Rat Rattus norvegicus Q80WA4 474 48425 S24 I D L D P P D S R K R P L E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIQ3 427 47260
Frog Xenopus laevis NP_001086143 484 49243 S25 I D L D P P D S R K R P L E A
Zebra Danio Brachydanio rerio Q9PW80 582 63333 S37 S A P F L V K S G Y A F V D C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731355 583 61176 P31 Q Q Q Q Q Q D P Q K L G Q Q F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790705 557 57218 S44 L N G D S C D S R K R P L E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.6 71.1 87 N.A. 72.3 72.9 N.A. N.A. 20.9 75.4 21.3 N.A. 36.1 N.A. N.A. 43.6
Protein Similarity: 100 91.6 78.8 88.5 N.A. 80.4 81 N.A. N.A. 36.3 83.3 34 N.A. 51.1 N.A. N.A. 56.9
P-Site Identity: 100 6.6 13.3 0 N.A. 60 60 N.A. N.A. 0 60 13.3 N.A. 13.3 N.A. N.A. 53.3
P-Site Similarity: 100 13.3 20 0 N.A. 80 80 N.A. N.A. 0 80 26.6 N.A. 40 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 10 0 0 0 0 10 0 0 0 28 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % C
% Asp: 10 28 0 37 0 10 55 0 0 0 0 0 0 19 0 % D
% Glu: 0 10 0 19 10 0 0 0 10 0 10 0 0 46 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 10 0 10 10 0 10 % F
% Gly: 0 0 10 0 0 0 10 0 10 10 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 28 0 0 10 10 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 10 0 10 0 10 0 0 55 0 10 0 0 0 % K
% Leu: 10 10 28 0 10 0 0 10 10 0 19 10 46 10 0 % L
% Met: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 19 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 19 0 28 37 10 10 0 10 0 46 0 0 0 % P
% Gln: 10 10 10 10 10 10 0 19 10 0 0 0 10 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 46 0 46 0 0 0 0 % R
% Ser: 10 0 10 0 10 0 0 55 0 0 0 0 10 0 0 % S
% Thr: 10 0 0 0 0 10 10 0 0 0 0 10 0 0 19 % T
% Val: 0 0 10 0 0 10 0 0 0 0 0 0 19 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _