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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOVA2 All Species: 26.36
Human Site: T452 Identified Species: 58
UniProt: Q9UNW9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNW9 NP_002507.1 492 49009 T452 K G E F L P G T R N R R V T I
Chimpanzee Pan troglodytes XP_524310 526 52655 T486 K G E F L P G T R N R R V T I
Rhesus Macaque Macaca mulatta XP_001114554 466 47476 T426 K G E F V P G T R N R K V T I
Dog Lupus familis XP_855043 549 55157 T509 K G E F L P G T R N R R V T I
Cat Felis silvestris
Mouse Mus musculus Q9JKN6 507 51737 T467 K G E F V P G T R N R K V T I
Rat Rattus norvegicus Q80WA4 474 48425 K434 G A R I Q I S K K G E F V P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZIQ3 427 47260 D388 S G A S I K I D E P L E G S E
Frog Xenopus laevis NP_001086143 484 49243 T444 K G E F V P G T R N R K V T I
Zebra Danio Brachydanio rerio Q9PW80 582 63333 D536 D Q T P D E N D Q V V V K I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731355 583 61176 T540 K G I F A P G T R N R I V T I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790705 557 57218 K511 G A K I Q I S K K N E Y V P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.6 71.1 87 N.A. 72.3 72.9 N.A. N.A. 20.9 75.4 21.3 N.A. 36.1 N.A. N.A. 43.6
Protein Similarity: 100 91.6 78.8 88.5 N.A. 80.4 81 N.A. N.A. 36.3 83.3 34 N.A. 51.1 N.A. N.A. 56.9
P-Site Identity: 100 100 86.6 100 N.A. 86.6 6.6 N.A. N.A. 6.6 86.6 0 N.A. 80 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. N.A. 20 100 6.6 N.A. 80 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 0 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 10 0 0 19 0 0 0 0 0 0 0 % D
% Glu: 0 0 55 0 0 10 0 0 10 0 19 10 0 0 10 % E
% Phe: 0 0 0 64 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 19 73 0 0 0 0 64 0 0 10 0 0 10 0 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 19 10 19 10 0 0 0 0 10 0 10 64 % I
% Lys: 64 0 10 0 0 10 0 19 19 0 0 28 10 0 0 % K
% Leu: 0 0 0 0 28 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 73 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 64 0 0 0 10 0 0 0 19 0 % P
% Gln: 0 10 0 0 19 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 64 0 64 28 0 0 0 % R
% Ser: 10 0 0 10 0 0 19 0 0 0 0 0 0 10 0 % S
% Thr: 0 0 10 0 0 0 0 64 0 0 0 0 0 64 10 % T
% Val: 0 0 0 0 28 0 0 0 0 10 10 10 82 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _