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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR3 All Species: 21.82
Human Site: S373 Identified Species: 34.29
UniProt: Q9UNX4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNX4 NP_006775.1 943 106099 S373 K S F D L I H S P H G E L K A
Chimpanzee Pan troglodytes XP_524820 715 79849 K177 S G K D T M V K W W D L D T Q
Rhesus Macaque Macaca mulatta XP_001113341 943 106178 S373 K S F D L I H S P Q G E L K A
Dog Lupus familis XP_540261 943 106340 S373 K S F D L I H S P Q G E L K A
Cat Felis silvestris
Mouse Mus musculus Q8BHB4 942 105757 S372 K S F D L I H S P Q G E L K A
Rat Rattus norvegicus NP_001101175 942 106054 S372 K S F D L I H S P Q G E L K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511524 938 103974 G368 K S F D L I R G P R G E V K A
Chicken Gallus gallus Q5ZIU8 657 72720 F119 D F H P Y G S F V A S G S L D
Frog Xenopus laevis NP_001085274 942 105947 C367 K S F D L F S C A K G E L K A
Zebra Danio Brachydanio rerio Q7ZUV2 694 75977 S156 A V R C L A F S P D G K W L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650705 922 103132 G356 K S I D V V L G Q N Q E L R V
Honey Bee Apis mellifera XP_624815 920 103453 L361 I M G R N G E L R I S I G L N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188240 693 77355 T155 G T I L R K G T D R V V S L Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_188791 955 106047 T366 S S F S F C P T A P K E S L G
Baker's Yeast Sacchar. cerevisiae Q12220 943 106324 T356 S K L E L V L T T S S N T I E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 98.4 93.4 N.A. 90.9 90.4 N.A. 76.9 20.6 73.2 20.3 N.A. 42.8 47.9 N.A. 42.1
Protein Similarity: 100 72.3 99.3 96.8 N.A. 95.8 95.9 N.A. 88.5 35.7 85.9 34.8 N.A. 65.3 67.1 N.A. 56.7
P-Site Identity: 100 6.6 93.3 93.3 N.A. 93.3 93.3 N.A. 73.3 0 66.6 33.3 N.A. 33.3 0 N.A. 0
P-Site Similarity: 100 13.3 93.3 93.3 N.A. 93.3 93.3 N.A. 80 0 66.6 40 N.A. 60 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 39.6 40.3 N.A.
Protein Similarity: N.A. N.A. N.A. 60.8 61 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 7 0 0 14 7 0 0 0 0 54 % A
% Cys: 0 0 0 7 0 7 0 7 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 60 0 0 0 0 7 7 7 0 7 0 7 % D
% Glu: 0 0 0 7 0 0 7 0 0 0 0 60 0 0 7 % E
% Phe: 0 7 54 0 7 7 7 7 0 0 0 0 0 0 0 % F
% Gly: 7 7 7 0 0 14 7 14 0 0 54 7 7 0 7 % G
% His: 0 0 7 0 0 0 34 0 0 7 0 0 0 0 0 % H
% Ile: 7 0 14 0 0 40 0 0 0 7 0 7 0 7 0 % I
% Lys: 54 7 7 0 0 7 0 7 0 7 7 7 0 47 0 % K
% Leu: 0 0 7 7 60 0 14 7 0 0 0 7 47 34 0 % L
% Met: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 7 0 7 0 0 7 % N
% Pro: 0 0 0 7 0 0 7 0 47 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 27 7 0 0 0 7 % Q
% Arg: 0 0 7 7 7 0 7 0 7 14 0 0 0 7 0 % R
% Ser: 20 60 0 7 0 0 14 40 0 7 20 0 20 0 0 % S
% Thr: 0 7 0 0 7 0 0 20 7 0 0 0 7 7 0 % T
% Val: 0 7 0 0 7 14 7 0 7 0 7 7 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 7 7 0 0 7 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _