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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR3 All Species: 20.61
Human Site: S393 Identified Species: 32.38
UniProt: Q9UNX4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNX4 NP_006775.1 943 106099 S393 N N L V E L Y S L N P S L P T
Chimpanzee Pan troglodytes XP_524820 715 79849 H193 C F K T M V G H R T E V W G L
Rhesus Macaque Macaca mulatta XP_001113341 943 106178 S393 N N L V E L Y S L N P S L P T
Dog Lupus familis XP_540261 943 106340 S393 N N L V E S Y S L H P S A P A
Cat Felis silvestris
Mouse Mus musculus Q8BHB4 942 105757 S392 N N L V E L Y S L N A S L P A
Rat Rattus norvegicus NP_001101175 942 106054 S392 N N L V E L Y S L S T S L P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511524 938 103974 S388 N N Q V E L V S V T P A Q P V
Chicken Gallus gallus Q5ZIU8 657 72720 R135 D I K L W D V R R K G C I F K
Frog Xenopus laevis NP_001085274 942 105947 T390 L E C F S L P T E P A P S G K
Zebra Danio Brachydanio rerio Q7ZUV2 694 75977 K172 A S D D S T V K L W D L I A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650705 922 103132 I381 L Y S L E A S I K T R K A T D
Honey Bee Apis mellifera XP_624815 920 103453 L377 N S I D L Y S L F I K E K D E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188240 693 77355 G171 D S T G R I L G C H G P S P H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_188791 955 106047 L384 L S L N N N S L E F Y S L K S
Baker's Yeast Sacchar. cerevisiae Q12220 943 106324 T375 P Y E K R D P T S P A P L K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 98.4 93.4 N.A. 90.9 90.4 N.A. 76.9 20.6 73.2 20.3 N.A. 42.8 47.9 N.A. 42.1
Protein Similarity: 100 72.3 99.3 96.8 N.A. 95.8 95.9 N.A. 88.5 35.7 85.9 34.8 N.A. 65.3 67.1 N.A. 56.7
P-Site Identity: 100 0 100 73.3 N.A. 86.6 80 N.A. 53.3 0 6.6 6.6 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 6.6 100 80 N.A. 86.6 86.6 N.A. 66.6 20 13.3 20 N.A. 13.3 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 39.6 40.3 N.A.
Protein Similarity: N.A. N.A. N.A. 60.8 61 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 7 0 0 0 0 20 7 14 7 14 % A
% Cys: 7 0 7 0 0 0 0 0 7 0 0 7 0 0 0 % C
% Asp: 14 0 7 14 0 14 0 0 0 0 7 0 0 7 7 % D
% Glu: 0 7 7 0 47 0 0 0 14 0 7 7 0 0 7 % E
% Phe: 0 7 0 7 0 0 0 0 7 7 0 0 0 7 0 % F
% Gly: 0 0 0 7 0 0 7 7 0 0 14 0 0 14 7 % G
% His: 0 0 0 0 0 0 0 7 0 14 0 0 0 0 7 % H
% Ile: 0 7 7 0 0 7 0 7 0 7 0 0 14 0 0 % I
% Lys: 0 0 14 7 0 0 0 7 7 7 7 7 7 14 14 % K
% Leu: 20 0 40 14 7 40 7 14 40 0 0 7 40 0 7 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 47 40 0 7 7 7 0 0 0 20 0 0 0 0 7 % N
% Pro: 7 0 0 0 0 0 14 0 0 14 27 20 0 47 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 0 0 0 14 0 0 7 14 0 7 0 0 0 0 % R
% Ser: 0 27 7 0 14 7 20 40 7 7 0 40 14 0 7 % S
% Thr: 0 0 7 7 0 7 0 14 0 20 7 0 0 7 20 % T
% Val: 0 0 0 40 0 7 20 0 7 0 0 7 0 0 7 % V
% Trp: 0 0 0 0 7 0 0 0 0 7 0 0 7 0 0 % W
% Tyr: 0 14 0 0 0 7 34 0 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _