Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTF2 All Species: 18.48
Human Site: S455 Identified Species: 33.89
UniProt: Q9UNY4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNY4 NP_003585.3 1162 129588 S455 Q E L E E V L S G L T L S P E
Chimpanzee Pan troglodytes XP_513683 1162 129565 S455 Q E L E E V L S G L T L S P E
Rhesus Macaque Macaca mulatta XP_001112999 1163 129401 S456 Q E L E E A L S G L A L S P E
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q5NC05 1138 125512 S431 Q A L E D A L S A L A L S P E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416595 1178 129334 I456 A A L S A L N I S T T D T I E
Frog Xenopus laevis NP_001084942 1187 131668 S462 Q D L E D A L S S L S L S P E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P34739 1061 118357 E383 L D W D E L S E A V N E I K P
Honey Bee Apis mellifera XP_393754 954 109196 N295 D K F D S S Y N S D Y I S S K
Nematode Worm Caenorhab. elegans NP_502137 1091 122548 T391 F P S G S V M T Q N G L L P K
Sea Urchin Strong. purpuratus XP_787293 600 68137
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIY7 1277 144314 N435 V A K W K V P N I V R F S T K
Baker's Yeast Sacchar. cerevisiae P31244 790 91412 T130 A R K K K K K T S T K K K S P
Red Bread Mold Neurospora crassa Q7S1P9 1222 137173 L430 K D A R K D L L E A A D S A E
Conservation
Percent
Protein Identity: 100 99.1 95.8 N.A. N.A. 70.3 N.A. N.A. N.A. 53.5 51 N.A. N.A. 32.1 31.8 28.3 26.8
Protein Similarity: 100 99.4 96.9 N.A. N.A. 79.6 N.A. N.A. N.A. 66.2 66.8 N.A. N.A. 51.2 49.3 48.5 37.3
P-Site Identity: 100 100 86.6 N.A. N.A. 66.6 N.A. N.A. N.A. 20 66.6 N.A. N.A. 6.6 6.6 20 0
P-Site Similarity: 100 100 86.6 N.A. N.A. 73.3 N.A. N.A. N.A. 33.3 86.6 N.A. N.A. 33.3 40 40 0
Percent
Protein Identity: N.A. N.A. N.A. 23.1 21.3 21.3
Protein Similarity: N.A. N.A. N.A. 42.6 37.8 39.9
P-Site Identity: N.A. N.A. N.A. 13.3 0 20
P-Site Similarity: N.A. N.A. N.A. 40 20 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 24 8 0 8 24 0 0 16 8 24 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 24 0 16 16 8 0 0 0 8 0 16 0 0 0 % D
% Glu: 0 24 0 39 31 0 0 8 8 0 0 8 0 0 54 % E
% Phe: 8 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 24 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 8 8 0 0 8 8 8 0 % I
% Lys: 8 8 16 8 24 8 8 0 0 0 8 8 8 8 24 % K
% Leu: 8 0 47 0 0 16 47 8 0 39 0 47 8 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 16 0 8 8 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 8 0 0 0 0 0 0 47 16 % P
% Gln: 39 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Q
% Arg: 0 8 0 8 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 8 8 16 8 8 39 31 0 8 0 62 16 0 % S
% Thr: 0 0 0 0 0 0 0 16 0 16 24 0 8 8 0 % T
% Val: 8 0 0 0 0 31 0 0 0 16 0 0 0 0 0 % V
% Trp: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _