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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTF2 All Species: 12.12
Human Site: S880 Identified Species: 22.22
UniProt: Q9UNY4 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNY4 NP_003585.3 1162 129588 S880 H E S R G N Q S G R S P N N P
Chimpanzee Pan troglodytes XP_513683 1162 129565 S880 H E S R G N Q S G R S P N N P
Rhesus Macaque Macaca mulatta XP_001112999 1163 129401 S881 H E S R G N Q S G R S P N N P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q5NC05 1138 125512 H856 Q E G R G S H H G R S P D N P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416595 1178 129334 H896 Q K N E S R E H A G S N P F E
Frog Xenopus laevis NP_001084942 1187 131668 R904 H E G G T H I R T Q N T D N P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P34739 1061 118357 S779 K F A R M A G S K K E V K S H
Honey Bee Apis mellifera XP_393754 954 109196 V686 L L S L H A D V K T H E I L V
Nematode Worm Caenorhab. elegans NP_502137 1091 122548 I802 D M K N H G F I P R R N R R A
Sea Urchin Strong. purpuratus XP_787293 600 68137 L332 L Q K L V K S L V L R R T K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIY7 1277 144314 A998 R A D S Q Q Y A D L D S L A R
Baker's Yeast Sacchar. cerevisiae P31244 790 91412 K522 D H P D L V L K R L N N F P G
Red Bread Mold Neurospora crassa Q7S1P9 1222 137173 S939 T A T T D D A S K T N N N F G
Conservation
Percent
Protein Identity: 100 99.1 95.8 N.A. N.A. 70.3 N.A. N.A. N.A. 53.5 51 N.A. N.A. 32.1 31.8 28.3 26.8
Protein Similarity: 100 99.4 96.9 N.A. N.A. 79.6 N.A. N.A. N.A. 66.2 66.8 N.A. N.A. 51.2 49.3 48.5 37.3
P-Site Identity: 100 100 100 N.A. N.A. 60 N.A. N.A. N.A. 6.6 26.6 N.A. N.A. 13.3 6.6 6.6 0
P-Site Similarity: 100 100 100 N.A. N.A. 73.3 N.A. N.A. N.A. 26.6 53.3 N.A. N.A. 33.3 6.6 6.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 23.1 21.3 21.3
Protein Similarity: N.A. N.A. N.A. 42.6 37.8 39.9
P-Site Identity: N.A. N.A. N.A. 0 0 13.3
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 8 0 0 16 8 8 8 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 8 8 8 8 8 0 8 0 8 0 16 0 8 % D
% Glu: 0 39 0 8 0 0 8 0 0 0 8 8 0 0 8 % E
% Phe: 0 8 0 0 0 0 8 0 0 0 0 0 8 16 0 % F
% Gly: 0 0 16 8 31 8 8 0 31 8 0 0 0 0 16 % G
% His: 31 8 0 0 16 8 8 16 0 0 8 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 8 8 0 0 0 0 8 0 0 % I
% Lys: 8 8 16 0 0 8 0 8 24 8 0 0 8 8 0 % K
% Leu: 16 8 0 16 8 0 8 8 0 24 0 0 8 8 0 % L
% Met: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 0 24 0 0 0 0 24 31 31 39 0 % N
% Pro: 0 0 8 0 0 0 0 0 8 0 0 31 8 8 39 % P
% Gln: 16 8 0 0 8 8 24 0 0 8 0 0 0 0 0 % Q
% Arg: 8 0 0 39 0 8 0 8 8 39 16 8 8 8 8 % R
% Ser: 0 0 31 8 8 8 8 39 0 0 39 8 0 8 0 % S
% Thr: 8 0 8 8 8 0 0 0 8 16 0 8 8 0 0 % T
% Val: 0 0 0 0 8 8 0 8 8 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _