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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTF2 All Species: 14.85
Human Site: S969 Identified Species: 27.22
UniProt: Q9UNY4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UNY4 NP_003585.3 1162 129588 S969 E L R D S E P S S T V S L N G
Chimpanzee Pan troglodytes XP_513683 1162 129565 S969 E L R D S E P S S T V S L N G
Rhesus Macaque Macaca mulatta XP_001112999 1163 129401 S970 E L R D S E P S S T V S L N G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q5NC05 1138 125512 S945 K V D V S E P S P T V S L N G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416595 1178 129334 K985 E L Q T P D S K S T V Y L N G
Frog Xenopus laevis NP_001084942 1187 131668 K993 E C Q G P D P K S T V S L N G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P34739 1061 118357 I868 L L P D E A R I A K A S K N L
Honey Bee Apis mellifera XP_393754 954 109196 F775 L T S K N P V F K S D R I S S
Nematode Worm Caenorhab. elegans NP_502137 1091 122548 T891 L E K T M N M T L G N G D N E
Sea Urchin Strong. purpuratus XP_787293 600 68137 D421 E M D G I E L D L V R Q M K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIY7 1277 144314 E1087 R T I L K R T E L I S C P T D
Baker's Yeast Sacchar. cerevisiae P31244 790 91412 M611 S I V S R L N M S G K W Q S S
Red Bread Mold Neurospora crassa Q7S1P9 1222 137173 S1028 D D D L E T S S T P G A S P E
Conservation
Percent
Protein Identity: 100 99.1 95.8 N.A. N.A. 70.3 N.A. N.A. N.A. 53.5 51 N.A. N.A. 32.1 31.8 28.3 26.8
Protein Similarity: 100 99.4 96.9 N.A. N.A. 79.6 N.A. N.A. N.A. 66.2 66.8 N.A. N.A. 51.2 49.3 48.5 37.3
P-Site Identity: 100 100 100 N.A. N.A. 66.6 N.A. N.A. N.A. 53.3 60 N.A. N.A. 26.6 0 6.6 13.3
P-Site Similarity: 100 100 100 N.A. N.A. 80 N.A. N.A. N.A. 66.6 73.3 N.A. N.A. 33.3 26.6 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.1 21.3 21.3
Protein Similarity: N.A. N.A. N.A. 42.6 37.8 39.9
P-Site Identity: N.A. N.A. N.A. 0 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 0 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 8 0 8 8 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 8 24 31 0 16 0 8 0 0 8 0 8 0 8 % D
% Glu: 47 8 0 0 16 39 0 8 0 0 0 0 0 0 24 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 16 0 0 0 0 0 16 8 8 0 0 47 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 8 0 0 8 0 8 0 0 8 0 0 % I
% Lys: 8 0 8 8 8 0 0 16 8 8 8 0 8 8 0 % K
% Leu: 24 39 0 16 0 8 8 0 24 0 0 0 47 0 8 % L
% Met: 0 8 0 0 8 0 8 8 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 8 8 8 0 0 0 8 0 0 62 0 % N
% Pro: 0 0 8 0 16 8 39 0 8 8 0 0 8 8 0 % P
% Gln: 0 0 16 0 0 0 0 0 0 0 0 8 8 0 0 % Q
% Arg: 8 0 24 0 8 8 8 0 0 0 8 8 0 0 0 % R
% Ser: 8 0 8 8 31 0 16 39 47 8 8 47 8 16 16 % S
% Thr: 0 16 0 16 0 8 8 8 8 47 0 0 0 8 0 % T
% Val: 0 8 8 8 0 0 8 0 0 8 47 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _