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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD1
All Species:
10
Human Site:
S10
Identified Species:
18.33
UniProt:
Q9UP38
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP38
NP_003496.1
647
71158
S10
E
E
E
A
P
K
K
S
R
A
A
G
G
G
A
Chimpanzee
Pan troglodytes
XP_519190
643
70814
S10
E
E
E
A
P
K
K
S
R
A
A
G
G
G
A
Rhesus Macaque
Macaca mulatta
XP_001092281
720
78423
A39
P
Q
G
P
R
L
P
A
S
A
A
P
A
G
A
Dog
Lupus familis
XP_539411
651
71536
S10
E
E
E
A
P
K
K
S
R
A
A
G
G
R
A
Cat
Felis silvestris
Mouse
Mus musculus
O70421
642
70937
E9
A
E
E
A
A
P
S
E
S
R
A
A
G
R
L
Rat
Rattus norvegicus
Q08463
641
71009
E9
A
E
E
A
V
P
S
E
S
R
A
A
G
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519817
718
80521
P95
L
P
T
A
L
F
L
P
S
E
L
W
H
L
L
Chicken
Gallus gallus
O57328
592
65472
G9
A
E
R
R
G
P
A
G
G
G
S
G
E
V
G
Frog
Xenopus laevis
Q9I9M5
559
62852
R9
K
H
S
H
L
L
Q
R
C
S
A
Q
L
C
T
Zebra Danio
Brachydanio rerio
NP_001124086
538
60387
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
T11
Q
I
L
F
I
L
P
T
L
I
Q
G
V
Q
R
Honey Bee
Apis mellifera
XP_623523
571
64519
Y8
M
I
P
R
Y
A
I
Y
V
F
S
V
A
V
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781961
563
63859
N8
M
G
W
L
V
R
E
N
R
H
L
A
V
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
86.3
96.4
N.A.
92.7
93
N.A.
65.8
81.9
75.4
70.3
N.A.
43.7
49.6
N.A.
50.7
Protein Similarity:
100
99.3
86.8
97
N.A.
93.8
93.8
N.A.
73.6
85.7
81.3
76.8
N.A.
56.8
61
N.A.
63.3
P-Site Identity:
100
100
26.6
93.3
N.A.
33.3
33.3
N.A.
6.6
13.3
6.6
0
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
100
40
93.3
N.A.
33.3
33.3
N.A.
6.6
20
26.6
0
N.A.
20
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
47
8
8
8
8
0
31
54
24
16
0
31
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
24
47
39
0
0
0
8
16
0
8
0
0
8
0
0
% E
% Phe:
0
0
0
8
0
8
0
0
0
8
0
0
0
0
16
% F
% Gly:
0
8
8
0
8
0
0
8
8
8
0
39
39
31
8
% G
% His:
0
8
0
8
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
16
0
0
8
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
24
24
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
8
16
24
8
0
8
0
16
0
8
8
16
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
8
8
8
24
24
16
8
0
0
0
8
0
0
8
% P
% Gln:
8
8
0
0
0
0
8
0
0
0
8
8
0
8
0
% Q
% Arg:
0
0
8
16
8
8
0
8
31
16
0
0
0
24
8
% R
% Ser:
0
0
8
0
0
0
16
24
31
8
16
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
16
0
0
0
8
0
0
8
16
16
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _