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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FZD1
All Species:
31.21
Human Site:
S233
Identified Species:
57.22
UniProt:
Q9UP38
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP38
NP_003496.1
647
71158
S233
L
C
V
G
Q
N
T
S
D
K
G
T
P
T
P
Chimpanzee
Pan troglodytes
XP_519190
643
70814
S229
L
C
V
G
Q
N
T
S
D
K
G
T
P
T
P
Rhesus Macaque
Macaca mulatta
XP_001092281
720
78423
S306
L
C
V
G
Q
N
T
S
D
K
G
T
P
T
P
Dog
Lupus familis
XP_539411
651
71536
S236
L
C
V
G
Q
N
T
S
D
K
G
T
P
T
P
Cat
Felis silvestris
Mouse
Mus musculus
O70421
642
70937
S228
L
C
V
G
Q
N
T
S
D
K
G
T
P
T
P
Rat
Rattus norvegicus
Q08463
641
71009
S227
L
C
V
G
Q
N
T
S
D
K
G
T
P
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519817
718
80521
S313
I
C
V
G
Q
N
H
S
E
D
G
A
P
A
L
Chicken
Gallus gallus
O57328
592
65472
S187
L
C
V
G
Q
N
A
S
E
R
G
T
P
T
P
Frog
Xenopus laevis
Q9I9M5
559
62852
T172
Q
N
T
T
E
S
G
T
P
T
P
A
V
P
E
Zebra Danio
Brachydanio rerio
NP_001124086
538
60387
V155
T
T
G
P
S
P
P
V
S
P
T
P
D
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18537
581
64829
T179
A
S
T
A
A
T
P
T
R
S
V
A
K
V
T
Honey Bee
Apis mellifera
XP_623523
571
64519
P171
M
P
V
A
E
F
Q
P
S
W
T
G
G
P
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781961
563
63859
N171
I
P
S
T
K
A
P
N
I
T
K
Q
T
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
86.3
96.4
N.A.
92.7
93
N.A.
65.8
81.9
75.4
70.3
N.A.
43.7
49.6
N.A.
50.7
Protein Similarity:
100
99.3
86.8
97
N.A.
93.8
93.8
N.A.
73.6
85.7
81.3
76.8
N.A.
56.8
61
N.A.
63.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
53.3
80
0
0
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
66.6
93.3
20
0
N.A.
6.6
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
8
8
8
0
0
0
0
24
0
16
8
% A
% Cys:
0
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
47
8
0
0
8
0
0
% D
% Glu:
0
0
0
0
16
0
0
0
16
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
62
0
0
8
0
0
0
62
8
8
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
47
8
0
8
0
8
% K
% Leu:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
62
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
8
0
8
24
8
8
8
8
8
62
16
54
% P
% Gln:
8
0
0
0
62
0
8
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% R
% Ser:
0
8
8
0
8
8
0
62
16
8
0
0
0
0
0
% S
% Thr:
8
8
16
16
0
8
47
16
0
16
16
54
8
54
16
% T
% Val:
0
0
70
0
0
0
0
8
0
0
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _