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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TFR2 All Species: 11.82
Human Site: S15 Identified Species: 23.64
UniProt: Q9UP52 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UP52 NP_003218.2 801 88755 S15 F Q R A Q Q L S P R S S Q T V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113151 672 74384
Dog Lupus familis XP_546952 806 88711 S15 L Q R T Q R L S P R P S Q T I
Cat Felis silvestris
Mouse Mus musculus Q9JKX3 798 88384 S15 L R R V Q Q W S P R P S Q T I
Rat Rattus norvegicus B2GUY2 798 88309 S15 L R K V Q Q W S P R P S Q T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516658 498 55112
Chicken Gallus gallus Q90997 776 85640 M17 N L F S V E P M S Y T R F S I
Frog Xenopus laevis NP_001089576 754 85283 R8 M A R K R S T R R T C L L I C
Zebra Danio Brachydanio rerio NP_001009916 783 85895 G16 I T G A A G G G A Q A N E G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91406 770 85483 T10 Y V G V G A Q T V S T S L T G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M1S8 705 77149
Baker's Yeast Sacchar. cerevisiae P47161 811 91999 E14 E R K R E K E E G Q L K E R T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 81.9 87 N.A. 84.5 83.5 N.A. 32 38.8 26.8 49.8 N.A. N.A. N.A. 22.6 N.A.
Protein Similarity: 100 N.A. 82.6 91.8 N.A. 89.8 89.5 N.A. 44.8 55.5 46.4 65 N.A. N.A. N.A. 41.4 N.A.
P-Site Identity: 100 N.A. 0 66.6 N.A. 60 53.3 N.A. 0 0 6.6 13.3 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 100 N.A. 0 80 N.A. 73.3 73.3 N.A. 0 33.3 13.3 40 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. 40.5 39.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 17 9 9 0 0 9 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 9 9 9 9 0 0 0 0 17 0 0 % E
% Phe: 9 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 17 0 9 9 9 9 9 0 0 0 0 9 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 9 34 % I
% Lys: 0 0 17 9 0 9 0 0 0 0 0 9 0 0 0 % K
% Leu: 25 9 0 0 0 0 17 0 0 0 9 9 17 0 0 % L
% Met: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 34 0 25 0 0 0 0 % P
% Gln: 0 17 0 0 34 25 9 0 0 17 0 0 34 0 0 % Q
% Arg: 0 25 34 9 9 9 0 9 9 34 0 9 0 9 0 % R
% Ser: 0 0 0 9 0 9 0 34 9 9 9 42 0 9 0 % S
% Thr: 0 9 0 9 0 0 9 9 0 9 17 0 0 42 9 % T
% Val: 0 9 0 25 9 0 0 0 9 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _