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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFR2
All Species:
13.64
Human Site:
S19
Identified Species:
27.27
UniProt:
Q9UP52
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UP52
NP_003218.2
801
88755
S19
Q
Q
L
S
P
R
S
S
Q
T
V
Y
Q
R
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113151
672
74384
Dog
Lupus familis
XP_546952
806
88711
S19
Q
R
L
S
P
R
P
S
Q
T
I
Y
K
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKX3
798
88384
S19
Q
Q
W
S
P
R
P
S
Q
T
I
Y
R
R
V
Rat
Rattus norvegicus
B2GUY2
798
88309
S19
Q
Q
W
S
P
R
P
S
Q
T
I
Y
R
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516658
498
55112
Chicken
Gallus gallus
Q90997
776
85640
R21
V
E
P
M
S
Y
T
R
F
S
I
A
R
Q
T
Frog
Xenopus laevis
NP_001089576
754
85283
L12
R
S
T
R
R
T
C
L
L
I
C
L
T
M
T
Zebra Danio
Brachydanio rerio
NP_001009916
783
85895
N20
A
G
G
G
A
Q
A
N
E
G
V
E
E
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91406
770
85483
S14
G
A
Q
T
V
S
T
S
L
T
G
A
P
M
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M1S8
705
77149
Baker's Yeast
Sacchar. cerevisiae
P47161
811
91999
K18
E
K
E
E
G
Q
L
K
E
R
T
V
V
N
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
81.9
87
N.A.
84.5
83.5
N.A.
32
38.8
26.8
49.8
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
100
N.A.
82.6
91.8
N.A.
89.8
89.5
N.A.
44.8
55.5
46.4
65
N.A.
N.A.
N.A.
41.4
N.A.
P-Site Identity:
100
N.A.
0
73.3
N.A.
73.3
73.3
N.A.
0
0
0
6.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
0
93.3
N.A.
86.6
86.6
N.A.
0
40
6.6
40
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26
21.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
9
0
0
0
0
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
9
9
9
0
0
0
0
17
0
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
9
9
9
9
0
0
0
0
9
9
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
34
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
9
0
0
0
0
9
0
0
% K
% Leu:
0
0
17
0
0
0
9
9
17
0
0
9
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
17
9
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% N
% Pro:
0
0
9
0
34
0
25
0
0
0
0
0
9
0
0
% P
% Gln:
34
25
9
0
0
17
0
0
34
0
0
0
9
9
0
% Q
% Arg:
9
9
0
9
9
34
0
9
0
9
0
0
25
34
0
% R
% Ser:
0
9
0
34
9
9
9
42
0
9
0
0
0
0
0
% S
% Thr:
0
0
9
9
0
9
17
0
0
42
9
0
9
0
17
% T
% Val:
9
0
0
0
9
0
0
0
0
0
17
9
9
0
42
% V
% Trp:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
34
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _